Kovaleva V L, Drozhzhina T A
Biull Eksp Biol Med. 1978 May;85(5):580-2.
Inhibition of leukocyte migration was studied in 40 patients with trophoblastic tumours under the effect of protein extract from chorionepithelioma. A marked inhibition of leukocyte migration was revealed in patients with signs of active tumour process before and during the treatment. Four patients in whom no inhibition was revealed either before or during the treatment were an exception. In the majority of the patients the inhibition effect was absent against the background of clinical well-being achieved as a result of surgical and chemotherapeutic, or chemotherapeutic treatment alone. Leukocytes of healthy donors failed to respond to the tumour extract in all 24 cases.
在绒毛膜上皮癌蛋白提取物的作用下，对40例滋养层细胞瘤患者的白细胞迁移抑制情况进行了研究。在治疗前和治疗期间有肿瘤活动迹象的患者中，发现白细胞迁移受到显著抑制。有4例患者在治疗前和治疗期间均未发现抑制现象，属于例外情况。在大多数患者中，在通过手术和化疗或仅通过化疗实现临床康复的情况下，未出现抑制作用。在所有24例病例中，健康供者的白细胞对肿瘤提取物均无反应。
