Division of Community Health Sciences, St George's, University of London, London, United Kingdom.
Am J Clin Nutr. 2010 Oct;92(4):776-83. doi: 10.3945/ajcn.2010.29533. Epub 2010 Aug 25.
Ischemic heart disease (IHD) rates are lower in UK black Africans and black Caribbeans and higher in South Asians when compared with white Europeans. Ethnic differences in lipid concentrations may play a part in these differences.
The objective was to investigate blood lipid and dietary patterns in UK children from different ethnic groups.
This was a cross-sectional study in 2026 UK children (including 285 black Africans, 188 black Caribbeans, 534 South Asians, and 512 white Europeans) attending primary schools in London, Birmingham, and Leicester. We measured fasting blood lipid concentrations and collected 24-h dietary recalls.
In comparison with white Europeans, black African children had lower total cholesterol (-0.14 mmol/L; 95% CI: -0.25, -0.04 mmol/L), LDL-cholesterol (-0.10 mmol/L; 95% CI: -0.20, -0.01 mmol/L), and triglyceride concentrations (proportional difference: -0.11 mmol/L; 95% CI: -0.16, -0.06 mmol/L); HDL-cholesterol concentrations were similar. Lower saturated fat intakes (-1.4%; 95% CI: -1.9%, -0.9%) explained the differences between total and LDL cholesterol. Black Caribbean children had total, LDL-cholesterol, HDL-cholesterol, and triglyceride concentrations similar to those for white Europeans, with slightly lower saturated fat intakes. South Asian children had total and LDL-cholesterol concentrations similar to those for white Europeans, lower HDL-cholesterol concentrations (-0.7 mmol/L; 95% CI: -0.11, -0.03 mmol/L), and elevated triglyceride concentrations (proportional difference: 0.14 mmol/L; 95% CI: 0.09, 0.20 mmol/L); higher polyunsaturated and monounsaturated fat intakes did not explain these lipid differences.
Only black African children had a blood lipid profile and associated dietary pattern likely to protect against future IHD. The loss of historically lower LDL-cholesterol concentrations among UK black Caribbeans and South Asians may have important adverse consequences for future IHD risk in these groups.
与白种欧洲人相比，英国黑非洲裔和黑加勒比裔人群的缺血性心脏病（IHD）发病率较低，而南亚裔人群的发病率则较高。血脂浓度的种族差异可能在这些差异中起一定作用。
本研究旨在调查不同族裔英国儿童的血脂和饮食模式。
这是一项在伦敦、伯明翰和莱斯特的 2026 名英国儿童（包括 285 名黑非洲人、188 名黑加勒比人、534 名南亚人和 512 名白种欧洲人）中进行的横断面研究。我们测量了空腹血脂浓度，并收集了 24 小时饮食记录。
与白种欧洲人相比，黑非洲儿童的总胆固醇（-0.14mmol/L；95%CI：-0.25，-0.04mmol/L）、LDL 胆固醇（-0.10mmol/L；95%CI：-0.20，-0.01mmol/L）和甘油三酯浓度较低（比例差异：-0.11mmol/L；95%CI：-0.16，-0.06mmol/L）；HDL 胆固醇浓度相似。较低的饱和脂肪摄入量（-1.4%；95%CI：-1.9%，-0.9%）解释了总胆固醇和 LDL 胆固醇之间的差异。黑加勒比儿童的总胆固醇、LDL 胆固醇、HDL 胆固醇和甘油三酯浓度与白种欧洲人相似，饱和脂肪摄入量略低。南亚儿童的总胆固醇和 LDL 胆固醇浓度与白种欧洲人相似，HDL 胆固醇浓度较低（-0.7mmol/L；95%CI：-0.11，-0.03mmol/L），甘油三酯浓度升高（比例差异：0.14mmol/L；95%CI：0.09，0.20mmol/L）；较高的多不饱和脂肪和单不饱和脂肪摄入量并不能解释这些血脂差异。
只有黑非洲儿童的血脂谱和相关饮食模式可能有助于预防未来的 IHD。英国黑加勒比裔和南亚裔人群 LDL 胆固醇浓度的历史下降可能对这些人群未来的 IHD 风险产生重要的不利影响。
