Taha Ruba, Al Hijji Ibrahim, El Omri Halima, Al-Laftah Fareed, Negm Riham, Yassin Mohammed, El Ayoubi Hanadi
Department of Hematology and Medical Oncology, Al Amal Hospital, Hamad Medical Corporation, Doha, Qatar.
Case Rep Oncol. 2010 Jul 10;3(2):234-239. doi: 10.1159/000318230.
Viral retinitis due to cytomegalovirus (CMV) infection is rare in patients with acute leukemia who did not receive hematopoietic stem cell transplantation. We report a case of CMV retinitis that developed in a 49-year-old patient with acute lymphoblastic leukemia. The patient was treated with salvage chemotherapy using a hyper-CVAD regimen and did not receive hematopoietic stem cell transplantation. The incidence of CMV retinitis in this subgroup of patients is not described in literature. He had a very complicated course during chemotherapy but was successfully treated, with preservation of visual acuity, and to date he is in complete remission. Interestingly, prior to CMV retinitis, the patient had been diagnosed with and treated for candida retinitis. This case shows the importance of eye examination and care in patients diagnosed with hematological malignancies.
在未接受造血干细胞移植的急性白血病患者中，由巨细胞病毒（CMV）感染引起的病毒性视网膜炎较为罕见。我们报告一例49岁急性淋巴细胞白血病患者发生CMV视网膜炎的病例。该患者接受了采用高强度CVAD方案的挽救性化疗，未接受造血干细胞移植。文献中未描述该亚组患者中CMV视网膜炎的发生率。他在化疗期间病程非常复杂，但经成功治疗后视力得以保留，迄今为止他处于完全缓解状态。有趣的是，在发生CMV视网膜炎之前，该患者曾被诊断出患有念珠菌性视网膜炎并接受了治疗。该病例显示了对诊断为血液系统恶性肿瘤的患者进行眼部检查和护理的重要性。
