单次静脉注射和肌肉注射1.0克头孢地嗪后的药代动力学。
The pharmacokinetics of cefodizime following intravenous and intramuscular administration of a single dose of 1.0 g.
作者信息
Bryskier A, Procyk T, Tremblay D, Lenfant B, Fourtillan J B
机构信息
Institut Roussel-Uclaf, Romainville, France.
出版信息
J Antimicrob Chemother. 1990 Nov;26 Suppl C:59-63. doi: 10.1093/jac/26.suppl_c.59.
PMID:2074252
Abstract
The pharmacokinetics and absolute bioavailability of cefodizime were determined after iv and im administration of a single 1.0 g dose in eight healthy volunteers. The absolute bioavailability of cefodizime after im injection of 1.0 g was 88% and 91% when determined by two different formulae.
摘要
在8名健康志愿者单次静脉注射和肌内注射1.0 g剂量的头孢地嗪后，测定了其药代动力学和绝对生物利用度。通过两种不同公式测定，肌内注射1.0 g头孢地嗪后的绝对生物利用度分别为88%和91%。
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