Liu Z
Third Affiliated Hospital, 3rd Military Medical University of PLA, Chongqing.
Zhonghua Er Bi Yan Hou Ke Za Zhi. 1990 Oct;25(5):271-2, 317.
This retrospective clinicopathologic study is to determine whether true vocal cord fixation produced by epidermoid carcinoma of larynx is an absolute contraindication of treatment by hemilaryngectomy. Serial sections of 19 hemilaryngectomy specimens were re-examined and clinical records of each patient reviewed. The microscopic view revealed that true vocal cord fixation was caused by the vocalis muscle invasion in 16 of the 19 patients. "Positive margins" concerned with recurrences were present in 4 cases. There were 3 local recurrences. The five-year survival rate in the series demonstrates a 68 percent (13/19) determinant survival rate and a 76 percent (13/17) actual survival rate. The results suggest that careful attention to the exact anatomical extent of the tumor should determine its surgical resectability. True vocal cord fixation itself should not exclude the possibility for total laryngectomy.
这项回顾性临床病理研究旨在确定喉表皮样癌导致的真性声带固定是否为半喉切除术治疗的绝对禁忌证。对19例半喉切除术标本的连续切片进行了重新检查,并回顾了每位患者的临床记录。显微镜观察显示,19例患者中有16例真性声带固定是由甲杓肌受侵所致。4例出现与复发相关的“切缘阳性”。有3例局部复发。该系列的五年生存率显示,决定性生存率为68%(13/19),实际生存率为76%(13/17)。结果表明,应仔细关注肿瘤的确切解剖范围以确定其手术可切除性。真性声带固定本身不应排除全喉切除术的可能性。