Bates D
Department of Neurology, University of Newcastle upon Tyne, UK.
Ups J Med Sci Suppl. 1990;48:173-87.
The epidemiological and biochemical evidence supporting a role of dietary lipids in Multiple Sclerosis is reviewed. The published controlled trials of omega six Polyunsaturated Fatty Acids including 172 patients with Acute Remitting Multiple Sclerosis are discussed and the results of recent study with omega three Polyunsaturated Fatty Acids in a Double Blind controlled study involving 312 patients are presented. It appears that there is a trend suggesting that the addition of omega six and omega three Polyunsaturated Fatty Acids to the diet of patients with Multiple Sclerosis results in a reduction of the severity and frequency of relapses and in a mild overall benefit in a two year period.
本文综述了支持膳食脂质在多发性硬化症中作用的流行病学和生化证据。讨论了已发表的关于ω-6多不饱和脂肪酸的对照试验，其中包括172例急性缓解型多发性硬化症患者，并展示了近期一项针对312例患者的ω-3多不饱和脂肪酸双盲对照研究的结果。似乎有一个趋势表明，在多发性硬化症患者的饮食中添加ω-6和ω-3多不饱和脂肪酸可导致复发的严重程度和频率降低，并在两年内带来轻微的总体益处。
