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[Treatment results using cefixime for bacterial respiratory tract infections].

作者信息

Leonhardt L

机构信息

Klinisches Institut für Allergien und Atemwegserkrankungen, Hannover, Germany.

出版信息

Infection. 1990;18 Suppl 3:S115-8. doi: 10.1007/BF01644627.

DOI:10.1007/BF01644627
PMID:2079368
Abstract

In a prospective open clinical trial 20 patients with the diagnosis bacterial respiratory tract infection and underlying chronic obstructive lung disease were treated for 13 to 17 days with 200 mg cefixime b. i. d. 14 of 16 evaluable patients were treated successfully. In one patient the clinical symptoms remained unchanged and in another patient cefixime treatment failed. Ten of the 16 evaluable patients showed a positive baseline culture. In nine of these patients the initially isolated pathogens could be eliminated. In one patient, in whom cefixime therapy failed, change of pathogens was noticed after the end of treatment. Four of the 20 patients treated with cefixime reported side effects (gastritis, three; fungal dermatitis, one). In the patient with fungal dermatitis cefixime therapy was stopped.

摘要

相似文献

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本文引用的文献

1
In vitro activities of 39 antimicrobial agents for Branhamella catarrhalis and comparison of results with different quantitative susceptibility test methods.39种抗菌药物对卡他布兰汉菌的体外活性及不同定量药敏试验方法结果的比较
Antimicrob Agents Chemother. 1988 Feb;32(2):259-61. doi: 10.1128/AAC.32.2.259.
2
Comparative, multicenter studies of cefixime and amoxicillin in the treatment of respiratory tract infections.头孢克肟与阿莫西林治疗呼吸道感染的对比性多中心研究。
Am J Med. 1988 Sep 16;85(3A):6-13. doi: 10.1016/0002-9343(88)90457-3.
3
Safety and efficacy of cefixime versus cefaclor in respiratory tract infections.
J Chemother. 1989 Aug;1(4):257-60. doi: 10.1080/1120009x.1989.11738903.
4
beta-Lactamase stability and in vitro activity of oral cephalosporins against strains possessing well-characterized mechanisms of resistance.β-内酰胺酶稳定性及口服头孢菌素对具有明确耐药机制菌株的体外活性。
Antimicrob Agents Chemother. 1989 Aug;33(8):1313-7. doi: 10.1128/AAC.33.8.1313.
5
Cefixime, in-vitro activity, pharmacokinetics and tissue penetration.
J Antimicrob Chemother. 1989 Feb;23(2):221-8. doi: 10.1093/jac/23.2.221.
6
Cefixime versus amoxicillin/clavulanic acid in lower respiratory tract infections.头孢克肟与阿莫西林/克拉维酸治疗下呼吸道感染的对比
Int J Clin Pharmacol Ther Toxicol. 1989 Jan;27(1):30-3.