US Naval Medical Research Unit No. 3, PSC 452, Box 5000, FPO AE 09835-9998.
Int J Antimicrob Agents. 2010 Nov;36 Suppl 1:S70-4. doi: 10.1016/j.ijantimicag.2010.06.026. Epub 2010 Aug 30.
With the increasing biological threat from emerging infectious diseases and bioterrorism, it has become essential for governments around the globe to increase awareness and preparedness for identifying and containing those agents. This article introduces the basic concepts of laboratory management, laboratory biosafety and laboratory biosecurity. Assessment criteria for laboratories' biorisk should include both biosafety and biosecurity measures. The assessment requires setting specific goals and selecting management approaches. In order to implement technologies at the laboratory working level, a management team should be created whose role is to implement biorisk policies, rules and regulations appropriate for that facility. Rules and regulations required by government authorities are presented, with special emphasis on methods for air control, and liquid and solid waste management. Management and biorisk measures and appropriate physical facilities must keep pace, ensuring efficient facilities that protect workers, the environment, the product (research, diagnostic and/or vaccine) and the biological pathogen.
随着新发传染病和生物恐怖主义带来的生物威胁不断增加，全球各国政府必须提高对识别和控制这些病原体的认识和准备。本文介绍了实验室管理、实验室生物安全和实验室生物安保的基本概念。实验室生物风险评估标准应包括生物安全和生物安保措施。评估需要设定具体目标并选择管理方法。为了在实验室工作层面实施技术，应创建一个管理团队，其作用是执行适用于该设施的生物风险政策、规则和法规。本文还介绍了政府当局规定的规则和法规，特别强调了空气控制以及液体和固体废物管理方法。管理和生物风险措施以及适当的物理设施必须齐头并进，确保设施高效，保护工人、环境、产品（研究、诊断和/或疫苗）和生物病原体。
