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三级生物安全实验室设施生物安全风险识别与分析研究

The study of biosafety risk identification and analysis for facilities in biosafety level 3 laboratories.

作者信息

Lv Bingwang, Zhou Zhiyu, Wang Jinsong, Niu Qun, Shi Yuchen, Sun Yanbo, Zhao Hongda, Lu Dongsheng, Fan Tao, Huang Yang

机构信息

National Institutes for Food and Drug Control, Beijing, China.

出版信息

Front Cell Infect Microbiol. 2025 Aug 27;15:1658759. doi: 10.3389/fcimb.2025.1658759. eCollection 2025.

DOI:10.3389/fcimb.2025.1658759
PMID:40937440
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12420197/
Abstract

OBJECTIVE

The aim of this study was to identify and analyze biosafety risk points in biosafety level 3 (BSL-3) laboratory facilities to bring awareness to the attention of administrative staff, reduce the biosafety risks, and improve the risk management.

METHODS

The biosafety risk points in BSL-3 facilities were identified by literature searches and field research methods, and the identified biosafety risk points subsequently analyzed using the fault analysis event tree method.

RESULTS & CONCLUSION: Throughout the comprehensive screening and identification of biosafety risk points in BSL-3 laboratory facilities, risk assessments were performed to rank their seriousness. This will help effectively reduce the biosafety risk level of BSL-3 laboratory facilities.

摘要

目的

本研究旨在识别和分析三级生物安全实验室（BSL-3）设施中的生物安全风险点，以引起管理人员的重视，降低生物安全风险，并改善风险管理。

方法

通过文献检索和实地调研方法识别BSL-3设施中的生物安全风险点，随后使用故障分析事件树方法对识别出的生物安全风险点进行分析。

结果与结论

通过对BSL-3实验室设施中的生物安全风险点进行全面筛选和识别，并进行风险评估以确定其严重程度。这将有助于有效降低BSL-3实验室设施的生物安全风险水平。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1262/12420197/a5cb704952c1/fcimb-15-1658759-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1262/12420197/77bc907e6c68/fcimb-15-1658759-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1262/12420197/040601e0c52e/fcimb-15-1658759-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1262/12420197/d38f1e11e5a3/fcimb-15-1658759-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1262/12420197/b5d84ba92d78/fcimb-15-1658759-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1262/12420197/50acff1f645e/fcimb-15-1658759-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1262/12420197/a5cb704952c1/fcimb-15-1658759-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1262/12420197/77bc907e6c68/fcimb-15-1658759-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1262/12420197/040601e0c52e/fcimb-15-1658759-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1262/12420197/d38f1e11e5a3/fcimb-15-1658759-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1262/12420197/b5d84ba92d78/fcimb-15-1658759-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1262/12420197/50acff1f645e/fcimb-15-1658759-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1262/12420197/a5cb704952c1/fcimb-15-1658759-g006.jpg

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