School of Physical and Occupational Therapy, Faculty of Medicine, McGill University, Montreal, QC, Canada.
Arch Phys Med Rehabil. 2010 Sep;91(9):1410-7. doi: 10.1016/j.apmr.2010.06.005.
To estimate, for persons with multiple sclerosis (MS), the extent to which peak oxygen consumption (Vo(2)peak) can be predicted by the results on submaximal tests.
Cross-sectional study.
Three MS clinics in the Greater Montreal region, Canada.
A center-stratified random sample of 135 women and 48 men was drawn (N=183). A subgroup of 59 subjects with MS, who were able to perform the step test, was selected from this sample to complete the maximal exercise test.
Not applicable.
Vo(2)peak.
In this sample (mean age +/- SD, 39 +/- 9 y; median Expanded Disability Status Scale=1.5), the mean Vo(2)peak +/- SD was 27.6 +/- 7.3 mL.kg(-1).min(-1). This value is considerably low when compared with healthy persons, ranking below the 25th percentile for both men and women. In a multivariate regression analysis, the step test and grip strength were identified as the only significant predictors of Vo(2)peak. When combined with body weight, grip strength and the step test explained 74% of the variance in Vo(2)peak.
Patients with MS with a mild degree of disability exhibit marked reductions in exercise capacity. Also, in persons with MS, submaximal tests are good predictors of exercise capacity. These measures may be used in clinical settings to help assess and monitor maximum oxygen consumption and in research to evaluate the effect of exercise-related interventions. Furthermore, they will allow people with MS to self-monitor their exercise capacity and be more actively engaged in taking charge of their fitness level.
评估多发性硬化症（MS）患者，最大摄氧量（Vo(2)peak）可通过亚极量测试结果预测的程度。
横断面研究。
加拿大蒙特利尔大都市区的 3 个 MS 诊所。
从该样本中抽取了 135 名女性和 48 名男性的中心分层随机样本（N=183）。从该样本中选择了 59 名能够进行台阶测试的 MS 患者亚组，以完成最大运动测试。
不适用。
Vo(2)peak。
在该样本中（平均年龄±SD，39±9 岁；扩展残疾状态量表中位数=1.5），Vo(2)peak 的平均值±SD 为 27.6±7.3 mL.kg(-1).min(-1)。与健康人相比，这个值明显较低，男性和女性均低于第 25 个百分位数。多元回归分析表明，台阶测试和握力是 Vo(2)peak 的唯一显著预测因子。当与体重、握力和台阶测试相结合时，它们解释了 Vo(2)peak 变异的 74%。
患有轻度残疾的 MS 患者表现出运动能力的显著降低。此外，在 MS 患者中，亚极量测试是运动能力的良好预测因子。这些措施可用于临床评估和监测最大摄氧量，并可用于评估与运动相关的干预措施的效果。此外，它们将使 MS 患者能够自我监测他们的运动能力，并更积极地参与管理他们的健康水平。
