Department of Gastroenterology, Hepatology, Infectiology, Neurogastroenterology, Hematology and Oncology, HELIOS-Clinic Krefeld, Krefeld, Germany.
Endoscopy. 2010 Nov;42(11):885-8. doi: 10.1055/s-0030-1255714. Epub 2010 Aug 27.
Push enteroscopy, balloon-guided, and single- and double-balloon enteroscopy (DBE) are now well established techniques in gastrointestinal endoscopy for small-bowel imaging and therapy. There are no published prospective studies comparing DBE with spiral enteroscopy and so the aim of the current study was to compare the performance of the two techniques in patients undergoing diagnostic enteroscopy.
Between January and December 2009, 35 patients referred for diagnostic enteroscopy were prospectively assigned to either spiral enteroscopy (n=18) or DBE (n=17). The performance of the two techniques was compared.
The patients were comparable with regard to age, sex, and indication for enteroscopy. Investigation performance, as assessed by time of insertion into the pylorus, the depth of insertion, the duration of the enteroscopy, and the amount of sedoanalgesia required were not significantly different between spiral enteroscopy and DBE. In 40% of the investigations, enteroscopy could detect abnormalities in the intestinal mucosa, in particular inflammatory changes and ulcers and, to a lesser extent, angiodysplasia. No significant difference in pathological findings could be detected between the two groups; however, clinically, diagnostic yield appeared to be higher for DBE (47.1% vs. 33.4%; n.s.).
Although this small study appears to show that DBE has a clinically higher diagnostic yield than spiral enteroscopy, larger studies are needed to confirm this preliminary finding.
经推式小肠镜、气囊引导式小肠镜和单气囊小肠镜（DBE）现已成为小肠内镜检查中小肠成像和治疗的成熟技术。目前尚无发表的前瞻性研究比较 DBE 与螺旋式小肠镜，因此本研究旨在比较两种技术在接受诊断性小肠镜检查的患者中的表现。
2009 年 1 月至 12 月期间，35 例因诊断性小肠镜而就诊的患者被前瞻性分配至螺旋式小肠镜（n=18）或 DBE（n=17）组。比较两种技术的性能。
两组患者在年龄、性别和小肠镜适应证方面具有可比性。插入幽门的时间、插入深度、小肠镜检查时间和所需镇静镇痛剂的量等评估的检查性能在螺旋式小肠镜和 DBE 之间无显著差异。在 40%的检查中，小肠镜可以检测到肠黏膜的异常，特别是炎症改变和溃疡，其次是血管扩张。两组之间的病理发现无显著差异；然而，从临床角度来看，DBE 的诊断率似乎更高（47.1% vs. 33.4%；n.s.）。
尽管本小样本研究似乎表明 DBE 的临床诊断率高于螺旋式小肠镜，但需要更大规模的研究来证实这一初步发现。
