预测医学、预防医学、个体化医学和参与医学：回归未来。
Predictive, preventive, personalized and participatory medicine: back to the future.
机构信息
Functional Genomics and Systems Biology for Health, CNRS Institute of Biological Sciences, 7 rue Guy Moquet, BP8, 94801 Villejuif cedex, France.
出版信息
Genome Med. 2010 Aug 26;2(8):57. doi: 10.1186/gm178.
Abstract
The pioneering work of Jean Dausset on the HLA system established several principles that were later reflected in the Human Genome Project and contributed to the foundations of predictive, preventive, personalized and participatory (P4) medicine. To effectively develop systems medicine, we should take advantage of the lessons of the HLA saga, emphasizing the importance of exploring a fascinating but mysterious biology, now using systems principles, pioneering new technology developments and creating shared biological and information resources.
摘要
让·多塞（Jean Dausset）在 HLA 系统方面的开创性工作确立了几项原则，这些原则后来反映在人类基因组计划中，并为预测性、预防性、个体化和参与性（P4）医学的基础做出了贡献。为了有效地发展系统医学，我们应该利用 HLA 传奇的经验教训，强调探索迷人但神秘的生物学的重要性，现在使用系统原理，开拓新的技术发展，并创建共享的生物和信息资源。
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