Department of Engineering Science, National Cheng Kung University, Tainan 70101, Taiwan.
Opt Lett. 2010 Sep 1;35(17):2937-9. doi: 10.1364/OL.35.002937.
We report a surface-enhanced Raman scattering (SERS) microchip that is capable of measuring SERS signals of liquid samples with high sensitivity. The microdevice is an integration of a silicon-based SERS substrate, a multimode optical fiber (MMF), and a microchannel embedded in the photosensitive glass fabricated by the femtosecond laser followed by thermal treatment, wet etching, and annealing. The performance of the SERS microchip is evaluated by measuring rhodamine 6G using a 632.8 nm He-Ne laser at 4.3 mW excitation power, which reveals that the detection limit is lower than 10(-10) M at a 1 s short accumulation time.
我们报告了一种表面增强拉曼散射（SERS）微芯片，该芯片能够以高灵敏度测量液体样品的 SERS 信号。该微器件是一种硅基 SERS 基底、多模光纤（MMF）和微通道的集成，该微通道嵌入在光敏玻璃中，由飞秒激光制造，然后经过热处理、湿法刻蚀和退火。通过使用 632.8nm He-Ne 激光在 4.3mW 激发功率下测量罗丹明 6G，评估了 SERS 微芯片的性能，结果表明在 1 秒短积分时间下检测限低于 10(-10)M。
