化脓性脑室炎合并嗜沫阿克曼菌感染性心内膜炎：一例病例报告并文献复习。
Pyogenic ventriculitis complicating Aggregatibacter aphrophilus infective endocarditis: A case report and literature review.
机构信息
Faculty of Medicine and Dentistry;
出版信息
Can J Infect Dis Med Microbiol. 2009 Fall;20(3):e107-9. doi: 10.1155/2009/971735.
Abstract
Pyogenic ventriculitis (PV) is an uncommon, but frequently fatal infection that results from inflammation of the ventricular ependymal lining associated with a purulent ventricular system. PV has been rarely reported as a secondary complication of infective endocarditis. Prompt diagnosis and treatment with appropriate culture-directed antibiotics with adequate central nervous system penetration is crucial when managing patients who are suspected of having PV. The present study reports on a fatal case of a previously well 42-year-old alcoholic woman with infective endocarditis caused by Aggregatibacter aphrophilus, with secondary brain abscess and spontaneous rupture into the ventricles causing PV.
摘要
化脓性脑室炎（PV）是一种不常见但常可致命的感染，由与化脓性脑室系统相关的室管膜内皮层炎症引起。PV 很少作为感染性心内膜炎的继发性并发症报道。当怀疑患者患有 PV 时，及时诊断和使用适当的、有针对性的培养抗生素进行治疗，并确保抗生素能充分穿透中枢神经系统，这至关重要。本研究报告了一例致命性病例，一名 42 岁的既往健康的酗酒女性，感染性心内膜炎由嗜沫嗜血杆菌引起，继发脑脓肿并自发性破裂入脑室导致 PV。
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