Department of Nutrition and Food Sciences, Physiology and Toxicology, Faculty of Pharmacy, University of Navarra, Irunlarrea 1, 31008 Pamplona, Navarra, Spain.
Biol Trace Elem Res. 2011 Oct;143(1):8-19. doi: 10.1007/s12011-010-8831-x. Epub 2010 Sep 1.
To assess the effects of a moderately high-protein intake on the body composition, biochemical, and antioxidant status parameters in young adults depending on either selenium- (Se) or non-enriched chicken consumption. The volunteers (n = 24) that completed the 10-week nutritional intervention were distributed in two parallel groups and randomly assigned to follow an isocaloric diet with moderately high content in protein (30% energy), either with the consumption of four 200 g portions/week of Se- or non-enriched chicken breasts. Blood samples were taken at the beginning and at the end of the study and body composition was monitored during the trial. There was a significant reduction in weight, accompanying a decrease on fat mass in both groups, while fat-free mass remained unchanged during the 10 weeks of intervention, without differences between both dietary groups. Selenium blood levels and plasma glutathione peroxidase activity, as well as lipid, glucose, and selected inflammation biomarkers remained stable during the intervention period in both dietary groups. Frequent chicken consumption, within a controlled diet with a moderately high content in protein, produced a slight but statistically significant weight reduction mainly due to the loss of fat mass. An extra Se supplementation (22 μg/day) in the Se-enriched chicken breast did not affect tachyphylactic antioxidant status of the participants neither inflammatory-related markers after weight loss.
评估在硒（Se）或非富集鸡肉摄入的情况下，高蛋白质摄入对年轻人的身体成分、生化和抗氧化状态参数的影响。完成 10 周营养干预的志愿者（n = 24）被分为两组平行组，并随机分配到遵循高蛋白质（30%能量）的等热量饮食中，每周食用四（4）份 200 克硒或非富集鸡胸肉。在研究开始和结束时采集血液样本，并在试验期间监测身体成分。两组均出现体重减轻，伴随体脂肪量减少，而在 10 周的干预期间，无脂体重保持不变，两组之间没有差异。硒血液水平和血浆谷胱甘肽过氧化物酶活性以及血脂、血糖和选定的炎症生物标志物在两组的饮食干预期间均保持稳定。在高蛋白质控制饮食中频繁食用鸡肉会导致体重轻微但统计学上显著减轻，主要是由于体脂肪量的减少。在富含硒的鸡胸肉中额外补充 22μg/天的硒不会影响参与者的脱敏抗氧化状态，也不会影响减肥后的炎症相关标志物。
