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黑素瘤患者及其家属对黑素瘤风险的个人归因。

Personal attributions for melanoma risk in melanoma-affected patients and family members.

机构信息

Department of Psychiatry and Behavioral Sciences, Memorial Sloan-Kettering Cancer Center, 641 Lexington Avenue, Seventh Floor, New York, NY 10022, USA.

出版信息

J Behav Med. 2011 Feb;34(1):53-63. doi: 10.1007/s10865-010-9286-4. Epub 2010 Sep 1.

Abstract

Personal attributions for cancer risk involve factors that individuals believe contribute to their risk for developing cancer. Understanding personal risk attributions for melanoma may dictate gene-environment melanoma risk communication strategies. We examined attributions for melanoma risk in a population-based sample of melanoma survivors, first degree family members, and family members who are also parents (N = 939). We conducted qualitative examination of open-ended risk attributions and logistic regression examining predictors (demographics, family member type, perceived risk) of the attributions reported (ultraviolet radiation [UVR] exposure, heredity/genetics, phenotype, personal melanoma history, miscellaneous). We found a predominance of risk attributions to UVR and heredity/genetics (80 and 45% of the sample, respectively). Those reporting higher education levels were more likely to endorse attributions to heredity/genetics, as well as to phenotype, than those of lower education levels. First-degree relatives and parent family members were more likely to endorse heredity/genetic attributions than melanoma survivors; melanoma survivors were more likely to endorse personal history of melanoma attributions compared to first-degree relatives and parent family members. These findings inform the development of risk communication interventions for melanoma families.

摘要

个人对癌症风险的归因涉及个人认为会导致其患癌症的因素。了解黑色素瘤的个人风险归因可能决定了基因-环境黑色素瘤风险沟通策略。我们在一个基于人群的黑色素瘤幸存者、一级亲属和也是父母的亲属(N=939)样本中检查了黑色素瘤风险的归因。我们对开放式风险归因进行了定性检查,并进行了逻辑回归分析,以检查报告归因的预测因素(人口统计学、亲属类型、感知风险)(紫外线辐射[UVR]暴露、遗传/遗传学、表型、个人黑色素瘤史、杂项)。我们发现,UVR 和遗传/遗传学的风险归因占主导地位(分别为 80%和 45%的样本)。与教育程度较低的人相比,受教育程度较高的人更有可能认同遗传/遗传学归因,以及表型归因。一级亲属和父母亲属比黑色素瘤幸存者更有可能认同遗传/遗传归因;与一级亲属和父母亲属相比,黑色素瘤幸存者更有可能认同个人黑色素瘤史归因。这些发现为黑色素瘤家族的风险沟通干预措施的制定提供了信息。

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