Hemmerle Michael J, Röpcke Bernd, Eggers Christian, Oades Robert D
Prof. Eggers-Stiftung, Essen, Germany.
Z Kinder Jugendpsychiatr Psychother. 2010 Sep;38(5):361-9. doi: 10.1024/1422-4917/a000060.
The Trialog project offers patients with early-onset schizophrenia (EOS) a two-year programme of residential outpatient care following discharge from a clinic. The programme aims to support their further recovery and independence and encompasses interactive and psycho-educational multifamily care, coping with persistent symptoms, development of socio-emotional competence, independent house keeping, and support of school and vocational training.
To evaluate psychopathology along with social and neuropsychological function for 12 participants over a period of 2 years. Their progress was compared with that of 12 EOS patients who did not attend Trialog following discharge.
Participants showed a significantly greater decrease of positive and negative symptoms, as opposed to an increase in positive symptoms in the comparison group. Measures of social function, neuropsychological indicators of memory, (selective) attention, and psychomotor speed improved more than in the comparison subjects. Neither group showed changes in measures of intelligence or in the subjective quality of life.
First analyses raise hope that monitoring participant performance in the programme of the "Trialog project" will improve the treatment and care of EOS-patients in the critical first years following the onset of schizophrenia.
“三联对话”项目为早发性精神分裂症（EOS）患者提供一个从诊所出院后为期两年的住院门诊护理项目。该项目旨在支持他们进一步康复和独立，包括互动式和心理教育多家庭护理、应对持续症状、发展社会情感能力、独立持家以及支持学校和职业培训。
在两年时间里对12名参与者的精神病理学以及社会和神经心理学功能进行评估。将他们的进展与12名出院后未参加“三联对话”项目的EOS患者的进展进行比较。
与对照组阳性症状增加相反，参与者的阳性和阴性症状显著减少。社会功能指标、记忆的神经心理学指标（选择性）注意力和精神运动速度比对照组改善得更多。两组在智力指标或主观生活质量方面均未显示出变化。
初步分析带来了希望，即监测“三联对话”项目中参与者的表现将改善精神分裂症发病后头几年关键时期EOS患者的治疗和护理。
