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老年腰椎管狭窄症患者术后长期预后的预测因素。

Predictors of long-term outcome in an elderly group after laminectomy for lumbar stenosis.

机构信息

Department of Neurosurgery, Evangelismos Hospital; and.

出版信息

J Neurosurg Spine. 2010 Sep;13(3):329-34. doi: 10.3171/2010.3.SPINE09487.

Abstract

OBJECT

This is a retrospective long-term outcome study of results after laminectomy for lumbar spinal stenosis in an elderly group of patients. The study was designed to evaluate possible demographic, comorbidity, and clinical prognosticators for pain reduction and functional improvement in this population. Because the assessment of functional outcome in the elderly is complicated by several specific factors, the use of outcome measurement parameters should be revised and refined. Moreover, despite numerous relevant studies, the results of various techniques remain equivocal, particularly among the elderly, which renders the implementation of focused studies necessary. New data could be used to refine patient selection and choice of technique to improve prognosis.

METHODS

During a 5-year period, lumbar laminectomies were performed in 182 elderly patients. Of these 182, 125 patients (68.8%) were followed up for a mean period of 60.8 months. The outcome was assessed by means of pain visual analog scale (VAS) pain score, Oswestry Disability Index (ODI), and patient satisfaction questionnaire, and results were correlated to demographic (age, sex), comorbidity (Charlson Comorbidity Index, diabetes, depression, and history of lumbar spine surgery), and clinical (main preoperative complaint, preoperative VAS score, and ODI) factors.

RESULTS

In terms of the VAS score, 106 patients (84.8%) exhibited improvement at follow-up. The corresponding ODI improvement rate was 69.6% (87 patients). The mean VAS and ODI differences were 5.1 and 29.1, respectively. One hundred two patients (81.6%) were satisfied with the results of the operation. Univariate analysis for possible prognostic factors revealed the significant influence of low-back pain on VAS score (p = 0.024) and ODI (p < 0.001) not improving, while the ODI was also affected by sex (females had a poorer outcome [p = 0.019]). In contrast, patient satisfaction was not related to any of the preoperative parameters recorded; nevertheless, it was strongly related to all functional measurements on follow-up.

CONCLUSIONS

Considering the methodological issues of such studies, particularly in elderly patients, the authors conclude that the ODI is more sensitive than the VAS score in assessing prognostic value and that patient satisfaction is difficult to prognosticate, underscoring the particularities that this population presents regarding functionality assessment. Considering the prognostic value of preoperative factors, a negative influence of low-back pain and female sex is reported.

摘要

目的

这是一项回顾性长期研究,旨在评估老年人群行腰椎减压术后的结果。该研究旨在评估可能影响该人群疼痛减轻和功能改善的人口统计学、合并症和临床预后因素。由于老年人的功能评估受到多种特定因素的影响,因此应修改和完善功能评估参数的使用。此外,尽管有大量相关研究,但各种技术的结果仍存在争议,特别是在老年人中,这使得有必要进行针对性研究。新数据可用于改善患者选择和技术选择,以改善预后。

方法

在 5 年期间,对 182 名老年患者进行了腰椎减压术。其中 125 例(68.8%)患者平均随访 60.8 个月。通过疼痛视觉模拟量表(VAS)评分、Oswestry 功能障碍指数(ODI)和患者满意度问卷评估结果,并将结果与人口统计学(年龄、性别)、合并症(Charlson 合并症指数、糖尿病、抑郁和腰椎手术史)和临床(主要术前主诉、术前 VAS 评分和 ODI)因素相关联。

结果

在 VAS 评分方面,106 例(84.8%)患者在随访时有所改善。相应的 ODI 改善率为 69.6%(87 例)。平均 VAS 和 ODI 差值分别为 5.1 和 29.1。102 例(81.6%)患者对手术结果满意。单因素分析显示,腰痛对 VAS 评分(p=0.024)和 ODI(p<0.001)无改善有显著影响,而 ODI 还受性别影响(女性预后较差 [p=0.019])。相反,患者满意度与术前记录的任何参数均无关,但与随访时的所有功能测量值密切相关。

结论

考虑到此类研究的方法学问题,特别是在老年患者中,作者认为 ODI 比 VAS 评分更能敏感地评估预后价值,而患者满意度难以预测,突出了该人群在功能评估方面的特殊性。考虑到术前因素的预后价值,报告了腰痛和女性性别有负面影响。

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