Clinical Research Unit for Anxiety and Depression, School of Psychiatry, University of New South Wales at St Vincent's Hospital, Sydney, Australia.
Aust N Z J Psychiatry. 2010 Sep;44(9):784-90. doi: 10.3109/00048671003781798.
Options for revising the DSM-IV Generalized Anxiety Disorder (GAD) diagnostic criteria have been made by the DSM-5 Anxiety, Obsessive-Compulsive, Post-traumatic and Dissociative Disorders Work Group. It has been proposed that renaming the disorder Generalized Worry Disorder, clarifying criterion A to emphasize the primacy of worry, reducing the duration required, altering the list of associated symptoms to reflect the concomitants of worry that are specific to GAD, and adding behavioural criteria could clarify the concept of chronic worry for clinicians and enhance the reliability of the diagnosis. The influence of the proposed changes on the prevalence and severity of cases is examined.
Data from a national survey and from a clinical data set were used to quantify the effect of the proposed changes.
Reducing the duration from 6 to 3 months and removing the clinical significance criterion raised the prevalence of GAD, whereas revising the associated symptoms and adding behavioural symptoms reduced the prevalence. With all the new options implemented, although the prevalence of the diagnosis rose by 9%, it was associated with similar levels of distress and impairment as DSM-IV cases.
There is preliminary evidence that the proposals may increase the prevalence of GAD but may not influence the severity of cases. The clinical utility, reliability and validity of the diagnosis remains to be established.
DSM-5 焦虑、强迫、创伤后和分离障碍工作组对 DSM-IV 广泛性焦虑障碍(GAD)的诊断标准进行了修订。有人提议将该障碍重新命名为广泛性担忧障碍,将标准 A 澄清为强调担忧的首要地位,缩短所需的持续时间,改变相关症状列表以反映 GAD 特有的担忧伴随症状,并添加行为标准,这可以为临床医生澄清慢性担忧的概念,并提高诊断的可靠性。本研究旨在考察这些提议的改变对病例的流行率和严重程度的影响。
本研究使用全国性调查和临床数据集的数据来量化提议改变的影响。
将持续时间从 6 个月缩短至 3 个月,并删除临床意义标准,提高了 GAD 的流行率,而修订相关症状并添加行为症状则降低了流行率。虽然所有新选项的实施使诊断的流行率增加了 9%,但其与 DSM-IV 病例的痛苦和损伤程度相似。
初步证据表明,这些建议可能会增加 GAD 的流行率,但可能不会影响病例的严重程度。该诊断的临床实用性、可靠性和有效性仍有待确定。