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来源于 Hailey-Hailey 病局限性外阴皮损,经他克莫司治疗后发生的鳞状细胞癌。

Squamous cell carcinoma arising from a localized vulval lesion of Hailey-Hailey disease after tacrolimus therapy.

机构信息

Department of Dermatology and Allergology, University Hospital, RWTH Aachen University, Aachen, Germany.

出版信息

Am J Obstet Gynecol. 2010 Sep;203(3):e5-7. doi: 10.1016/j.ajog.2010.06.041.

Abstract

Hailey-Hailey disease (HHD) is a rare, autosomal dominant intraepidermal blistering disorder characterized by recurrent vesicles and erosions affecting mostly the intertriginous areas. We report a case of HHD affecting exclusively the vulva from which an invasive squamous cell carcinoma developed after tacrolimus therapy.

摘要

Hailey-Hailey 病(HHD)是一种罕见的常染色体显性遗传性表皮内水疱病,其特征为复发性水疱和糜烂,主要影响皱褶部位。我们报告了一例仅累及外阴的 HHD 病例,在他克莫司治疗后发生侵袭性鳞状细胞癌。

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