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应用概率建模评估巴氏杀菌牛乳中的二恶英和类二恶英多氯联苯。

Exposure assessment of dioxins and dioxin-like PCBs in pasteurised bovine milk using probabilistic modelling.

机构信息

Biosystems Engineering, UCD School of Agriculture, Food Science and Veterinary Medicine, University College, Belfield, Dublin 4, Ireland.

出版信息

Chemosphere. 2010 Sep;81(4):509-16. doi: 10.1016/j.chemosphere.2010.07.038.

Abstract

Quantitative exposure assessment is a useful technique to investigate the risk from contaminants in the food chain. The objective of this study was to develop a probabilistic exposure assessment model for dioxins (PCDD/Fs) and dioxin-like PCBs (DL-PCBs) in pasteurised bovine milk. Mean dioxins and DL-PCBs (non-ortho and mono-ortho PCBs) concentrations (pg WHO-TEQ g(-1)) in bovine milk were estimated as 0.06 ± 0.07 pg WHO-TEQ g(-1) for dioxins and 0.08 ± 0.07 pg WHO-TEQ g(-1) for DL-PCBs using Monte Carlo simulation. The simulated model estimated mean exposure for dioxins was 0.19 ± 0.29 pg WHO-TEQ kg(-1)bw d(-1) and 0.14 ± 0.22 pg WHO-TEQ kg(-1) bw d(-1) and for DL-PCBs was 0.25 ± 0.30 pg WHO-TEQ kg(-1) bw d(-1) and 0.19 ± 0.22 pg WHO-TEQ kg(-1) bw d(-1) for men and women, respectively. This study showed that the mean dioxins and DL-PCBs exposure from consumption of pasteurised bovine milk is below the provisional maximum tolerable monthly intake of 70 pg TEQ kg(-1) bw month(-1) (equivalent of 2.3 pg TEQ kg(-1) bw d(-1)) recommended by the Joint FAO/WHO Expert Committee on Food Additives and Contaminants (JECFA). Results from this study also showed that the estimated dioxins and DL-PCBs concentration in pasteurised bovine milk is comparable to those reported in previous studies.

摘要

定量暴露评估是一种研究食物链中污染物风险的有用技术。本研究的目的是开发一种巴氏杀菌牛奶中二恶英(PCDD/Fs)和类二恶英多氯联苯(DL-PCBs)的概率暴露评估模型。使用蒙特卡罗模拟估计牛奶中二恶英和 DL-PCBs(非邻位和单邻位 PCB)的平均浓度(pg WHO-TEQ g(-1))分别为 0.06 ± 0.07 pg WHO-TEQ g(-1)和 0.08 ± 0.07 pg WHO-TEQ g(-1)。模拟模型估计二恶英的平均暴露量为 0.19 ± 0.29 pg WHO-TEQ kg(-1)bw d(-1)和 0.14 ± 0.22 pg WHO-TEQ kg(-1)bw d(-1),DL-PCBs 为 0.25 ± 0.30 pg WHO-TEQ kg(-1)bw d(-1)和 0.19 ± 0.22 pg WHO-TEQ kg(-1)bw d(-1),分别为男性和女性。本研究表明,消费巴氏杀菌牛奶中二恶英和 DL-PCBs 的平均暴露量低于食品添加剂和污染物联合专家委员会(JECFA)建议的暂定最大耐受每月摄入量 70 pg TEQ kg(-1)bw 月(-1)(相当于 2.3 pg TEQ kg(-1)bw d(-1))。本研究的结果还表明,巴氏杀菌牛奶中二恶英和 DL-PCBs 的估计浓度与先前研究报告的浓度相当。

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