Biosystems Engineering, UCD School of Agriculture, Food Science and Veterinary Medicine, University College, Belfield, Dublin 4, Ireland.
Chemosphere. 2010 Sep;81(4):509-16. doi: 10.1016/j.chemosphere.2010.07.038.
Quantitative exposure assessment is a useful technique to investigate the risk from contaminants in the food chain. The objective of this study was to develop a probabilistic exposure assessment model for dioxins (PCDD/Fs) and dioxin-like PCBs (DL-PCBs) in pasteurised bovine milk. Mean dioxins and DL-PCBs (non-ortho and mono-ortho PCBs) concentrations (pg WHO-TEQ g(-1)) in bovine milk were estimated as 0.06 ± 0.07 pg WHO-TEQ g(-1) for dioxins and 0.08 ± 0.07 pg WHO-TEQ g(-1) for DL-PCBs using Monte Carlo simulation. The simulated model estimated mean exposure for dioxins was 0.19 ± 0.29 pg WHO-TEQ kg(-1)bw d(-1) and 0.14 ± 0.22 pg WHO-TEQ kg(-1) bw d(-1) and for DL-PCBs was 0.25 ± 0.30 pg WHO-TEQ kg(-1) bw d(-1) and 0.19 ± 0.22 pg WHO-TEQ kg(-1) bw d(-1) for men and women, respectively. This study showed that the mean dioxins and DL-PCBs exposure from consumption of pasteurised bovine milk is below the provisional maximum tolerable monthly intake of 70 pg TEQ kg(-1) bw month(-1) (equivalent of 2.3 pg TEQ kg(-1) bw d(-1)) recommended by the Joint FAO/WHO Expert Committee on Food Additives and Contaminants (JECFA). Results from this study also showed that the estimated dioxins and DL-PCBs concentration in pasteurised bovine milk is comparable to those reported in previous studies.
定量暴露评估是一种研究食物链中污染物风险的有用技术。本研究的目的是开发一种巴氏杀菌牛奶中二恶英(PCDD/Fs)和类二恶英多氯联苯(DL-PCBs)的概率暴露评估模型。使用蒙特卡罗模拟估计牛奶中二恶英和 DL-PCBs(非邻位和单邻位 PCB)的平均浓度(pg WHO-TEQ g(-1))分别为 0.06 ± 0.07 pg WHO-TEQ g(-1)和 0.08 ± 0.07 pg WHO-TEQ g(-1)。模拟模型估计二恶英的平均暴露量为 0.19 ± 0.29 pg WHO-TEQ kg(-1)bw d(-1)和 0.14 ± 0.22 pg WHO-TEQ kg(-1)bw d(-1),DL-PCBs 为 0.25 ± 0.30 pg WHO-TEQ kg(-1)bw d(-1)和 0.19 ± 0.22 pg WHO-TEQ kg(-1)bw d(-1),分别为男性和女性。本研究表明,消费巴氏杀菌牛奶中二恶英和 DL-PCBs 的平均暴露量低于食品添加剂和污染物联合专家委员会(JECFA)建议的暂定最大耐受每月摄入量 70 pg TEQ kg(-1)bw 月(-1)(相当于 2.3 pg TEQ kg(-1)bw d(-1))。本研究的结果还表明,巴氏杀菌牛奶中二恶英和 DL-PCBs 的估计浓度与先前研究报告的浓度相当。