Meyer-Sabellek W, Schulte K L, Gotzen R
Department of Cardiology, Boehringer Mannheim GmbH, Mannheim, Germany.
J Hypertens Suppl. 1990 Dec;8(6):S3-10.
Non-invasive automatic 24-h indirect ambulatory monitoring of blood pressure and the heart rate was performed in 2010 subjects at the Department of Internal Medicine, Klinikum Steglitz, Free University of Berlin, Germany, from 1983 to 1990. Blood pressure profiles were obtained using seven different monitors, Pressurometer III (Del Mar Avionics), Physioport (Natic), Accutracker (Oxford), Blutdrucksystem (Medizintechnik), SL 5200, SL 90202 and SL 90207 (SpaceLabs). The monitors were equipped with auscultatory and/or oscillometric devices, provided accurate readings and were repeatedly used up to eight times in some patients. Up to 100 data points per 24 h provided diurnal blood pressure profiles for over 91% of the patients in clinical and non-clinical situations. Early identification of borderline hypertensives at risk of cardiovascular disease and detailed information on the efficacy of different antihypertensive regimens may in part justify the high costs of the monitors. Although disturbance to sleep remained a problem in more than 20% of the patients investigated, the new, lighter, quieter monitors (e.g. SpaceLabs 90207 at 380 g) were well received by patients and nurses. In the future, simultaneous registration with 24-h ECG may help in identifying the effects of different antihypertensive therapies on blood pressure variability and the periodicity of the heart rate.
1983年至1990年期间，在德国柏林自由大学施泰格利茨临床医院内科，对2010名受试者进行了无创自动24小时间接动态血压和心率监测。使用七种不同的监测仪获取血压数据，分别是Pressurometer III（德尔玛航空电子公司）、Physioport（纳蒂克公司）、Accutracker（牛津公司）、Blutdrucksystem（医疗技术公司）、SL 5200、SL 90202和SL 90207（太空实验室公司）。这些监测仪配备了听诊和/或示波装置，读数准确，部分患者重复使用多达八次。每24小时最多100个数据点为91%以上的患者提供了临床和非临床情况下的日间血压数据。早期识别有心血管疾病风险的临界高血压患者以及不同降压方案疗效的详细信息，可能在一定程度上证明了监测仪高昂成本的合理性。尽管在超过20%的受调查患者中，睡眠干扰仍然是一个问题，但新型、更轻便、更安静的监测仪（如重380克的太空实验室90207）受到了患者和护士的好评。未来，同步记录24小时心电图可能有助于确定不同降压疗法对血压变异性和心率周期性的影响。
