Hagenäs L, Plöen L, Ritzen E M, Ekwall H
Andrologia. 1977 Jul-Sep;9(3):250-4. doi: 10.1111/j.1439-0272.1977.tb01297.x.
In order to elucidate the mechanisms behind the deleterious effects on the germinal epithelium of experimental cryptorchidism the hypothesis that a leaking blood-testis barrier is the cause of the damage was tested. The permeability of the specialized inter-Sertoli cell junctions to lanthanum after experimental cryptorchidism for 0.5 to 12 days was studied in the rat. In none of the time periods studied lanthanum had penetrated beyond the inter-Sertoli cell junctions. A simple lanthanum immersion technique was used. Testes of 15-days old rats (before the development of the barrier) were used as a positive control of the method, and in these testes lanthanum had penetrated up to the future lumen.
为了阐明实验性隐睾症对生精上皮产生有害影响的背后机制，对血睾屏障渗漏是损伤原因这一假说进行了验证。在大鼠中研究了实验性隐睾症持续0.5至12天后，支持细胞间特殊连接对镧的通透性。在研究的任何时间段内，镧都未穿透支持细胞间连接。采用了一种简单的镧浸入技术。15日龄大鼠（屏障发育前）的睾丸用作该方法的阳性对照，在这些睾丸中镧已穿透至未来的管腔。
