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[牡丹籽的化学成分]

[Chemical constituents from seeds of Paeonia suffruticosa].

作者信息

He Chunnian, Xiao Wei, Li Min, Peng Yong, Xu Lijia, Gu Jing, Xiao Peigen

机构信息

Institute of Medicinal Plant Development, Chinese Academy of Medical Science, Peking Union Medical College, Beijing 100193, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2010 Jun;35(11):1428-31.

Abstract

OBJECTIVE

To study the chemical constituents from seeds of Paeonia sufruticosa.

METHOD

Various chromatographic techniques were used to isolate and purify the constituents, their physico-chemical properties and spectral data were employed to elucidate their structures.

RESULT

Thirteen compounds were isolated and identified as: paeoniflorin (1), oxypaeoniflorin (2), 6'-O-beta-D-glucopyranosylalbiflorin (3), 8-debenzoylpaeoniflorin (4), 8-debenzoylpaeonidanin (5), 1-O-beta-D-glucopyranosylpaeonisuf-frone (6), 1-O-beta-D-ethyl-mannopyranoside (7), sucrose (8), luteolin (9), apigenin (10), benzoic acid (11) and 1-0-beta-D-(4-hydroxybenzoyl) glucose (12).

CONCLUSION

compounds 2, 4-6 were isolated from this plant for the first time, compounds 7 and 12 were isolated from the family of Paeoniaceae for the first time.

摘要

目的

研究牡丹籽的化学成分。

方法

采用多种色谱技术分离纯化各成分,利用其理化性质和光谱数据阐明结构。

结果

分离鉴定出13个化合物,分别为芍药苷(1)、氧化芍药苷(2)、6'-O-β-D-吡喃葡萄糖基芍药内酯苷(3)、8-去苯甲酰基芍药苷(4)、8-去苯甲酰基芍药新苷(5)、1-O-β-D-吡喃葡萄糖基芍药酮(6)、1-O-β-D-乙基甘露糖苷(7)、蔗糖(8)、木犀草素(9)、芹菜素(10)、苯甲酸(11)和1-O-β-D-(4-羟基苯甲酰基)葡萄糖(12)。

结论

化合物2、4 - 6为首次从该植物中分离得到,化合物7和12为首次从芍药科植物中分离得到。

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