牡丹籽油对衰老小鼠的抗氧化作用。
Antioxidant effect of peony seed oil on aging mice.
作者信息
Han Xiao-Miao, Wu Su-Xi, Wu Mei-Fang, Yang Xue-Feng
机构信息
1School of Chemistry and Bioengineering, Changsha University of Science and Technology, Changsha, 410004 China.
Haorui Biological Technology Co., Ltd, Changsha, 410004 China.
出版信息
Food Sci Biotechnol. 2017 Dec 12;26(6):1703-1708. doi: 10.1007/s10068-017-0225-9. eCollection 2017.
d-galactose was injected into mice of ages 4-5 months, and peony seed oil was administered using an oral gavage to assess its possible anti-aging functions. The content of malondialdehyde (MDA) and the activities of monoamine oxidase (MAO), glutathione peroxidase (GSH-Px), and superoxide dismutase (SOD) in the brain and liver of these mice were determined using biochemical kits. The significance of the differences in the content of the components associated with aging and anti-aging among each group was analyzed statistically. The MDA content and activities of MAO in the brain and liver of mice in the peony seed oil group were significantly lower than those in the aging group. The activities of GSH-Px, Cu/Zn-SOD, and Mn-SOD in the brain and liver of mice in the peony seed oil group were very significantly higher than those in the aging group. Peony seed oil was determined to have an obvious anti-aging function.
将d-半乳糖注射到4至5个月大的小鼠体内，并通过灌胃给予牡丹籽油，以评估其可能的抗衰老功能。使用生化试剂盒测定这些小鼠大脑和肝脏中丙二醛（MDA）的含量以及单胺氧化酶（MAO）、谷胱甘肽过氧化物酶（GSH-Px）和超氧化物歧化酶（SOD）的活性。对每组中与衰老和抗衰老相关成分含量的差异显著性进行统计学分析。牡丹籽油组小鼠大脑和肝脏中MDA含量及MAO活性显著低于衰老组。牡丹籽油组小鼠大脑和肝脏中GSH-Px、铜/锌超氧化物歧化酶（Cu/Zn-SOD）和锰超氧化物歧化酶（Mn-SOD）的活性极显著高于衰老组。确定牡丹籽油具有明显的抗衰老功能。
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