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感染性颞下颌关节全关节假体的管理

Management of the infected temporomandibular joint total joint prosthesis.

作者信息

Wolford Larry M, Rodrigues Daniel B, McPhillips Andrea

机构信息

Department of Oral and Maxillofacial Surgery, Texas A&M University Health Science Center, Baylor College of Dentistry, Dallas, TX, USA.

出版信息

J Oral Maxillofac Surg. 2010 Nov;68(11):2810-23. doi: 10.1016/j.joms.2010.05.089. Epub 2010 Sep 6.

Abstract

PURPOSE

Patients with specific temporomandibular joint (TMJ) conditions and pathology may benefit from TMJ reconstruction by use of total joint prostheses. A potential risk to patients receiving TMJ total joint prostheses is infection. The purpose of this study was to present our experience in treating infected TMJ total joint prostheses over a 12-year period, as well as the protocol we have developed to manage acute infections and the protocol we follow for chronic infections of TMJ total joint prostheses.

PATIENTS AND METHODS

This retrospective study evaluated the records of 316 consecutive patients (290 female and 26 male patients) who had TMJ reconstruction from 1997 to 2009 by 1 surgeon, using patient-fitted TMJ Concepts total joint prostheses (TMJ Concepts, Ventura, CA), with a total of 579 prostheses placed, to determine the occurrence and management methods of postoperative infections. Postoperative infections involving the TMJ prostheses developed in 8 of 316 patients (2.5%) and 9 of 579 prostheses (1.6%): 7 patients unilaterally and 1 patient bilaterally. Patients were divided into 2 groups: group 1 (n = 5) had acute infections in 6 joints and group 2 (n = 3) had chronic infections in 3 joints. Patient 5 began in group 1 but was transferred to group 2. One patient with Munchausen syndrome and self-induced infections was eliminated from the study. Patients were treated by our protocol for management of acute or chronic infections.

RESULTS

In group 1 (n = 5) the onset of infection symptoms averaged 12 days after surgery (range, 5-24 days). The time from onset of symptoms to surgical intervention was 3.4 days (range, 2-5 days). We found that 4 of 5 patients (80%) and 5 of 6 joints (83%) were successfully treated with retention of the prostheses. Patient 5 varied from the protocol and maintained a chronic infection of her right TMJ prosthesis that transferred her to group 2. In group 2 (n = 3) all 3 patients (including patient 5) had chronic infections with draining fistulas that were successfully treated by the chronic infection protocol including prosthesis removal and replacement.

CONCLUSIONS

TMJ total joint prostheses can become infected. The earlier the diagnosis is made and the acute infection protocol initiated (within 2-5 days), the greater the chance of salvage of the prosthesis. For chronic infections, the treatment protocol has likewise been very successful, but it does require 2 surgical stages for removal and replacement of the prosthesis. Management of infected total joint prosthesis can be challenging, but with aggressive treatment following the appropriate protocol, infected prostheses can be successfully managed.

摘要

目的

患有特定颞下颌关节(TMJ)疾病和病理状况的患者可能受益于使用全关节假体进行的TMJ重建。接受TMJ全关节假体的患者面临的一个潜在风险是感染。本研究的目的是介绍我们在12年期间治疗感染的TMJ全关节假体的经验,以及我们制定的管理急性感染的方案和针对TMJ全关节假体慢性感染所遵循的方案。

患者与方法

这项回顾性研究评估了1997年至2009年由1名外科医生使用患者适配的TMJ Concepts全关节假体(TMJ Concepts,加利福尼亚州文图拉)对316例连续患者(290例女性和26例男性患者)进行TMJ重建的记录,共植入579个假体,以确定术后感染的发生率和管理方法。316例患者中有8例(2.5%)和579个假体中有9个(1.6%)发生了涉及TMJ假体的术后感染:7例患者为单侧感染,1例患者为双侧感染。患者分为2组:第1组(n = 5)6个关节发生急性感染,第2组(n = 3)3个关节发生慢性感染。患者5最初在第1组,但后来转入第2组。1例患有孟乔森综合征并自我诱导感染的患者被排除在研究之外。患者按照我们的急性或慢性感染管理方案进行治疗。

结果

在第1组(n = 5)中,感染症状的出现平均在术后12天(范围为5 - 24天)。从症状出现到手术干预的时间为3.4天(范围为2 - 5天)。我们发现5例患者中有4例(80%)和6个关节中有5个(83%)通过保留假体成功治疗。患者5未按方案治疗,其右TMJ假体持续慢性感染,因此转入第2组。在第2组(n = 3)中,所有3例患者(包括患者5)均有伴有引流瘘的慢性感染,通过包括取出和更换假体的慢性感染方案成功治疗。

结论

TMJ全关节假体可能会被感染。诊断越早并启动急性感染方案(在2 - 5天内),假体挽救的机会就越大。对于慢性感染,治疗方案同样非常成功,但确实需要2个手术阶段来取出和更换假体。感染的全关节假体的管理可能具有挑战性,但遵循适当的方案进行积极治疗,可以成功管理感染的假体。

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