Department of Interventional Cardiology, Thoraxcenter, Erasmus University MC, Rotterdam, The Netherlands.
Catheter Cardiovasc Interv. 2011 May 1;77(6):798-806. doi: 10.1002/ccd.22767. Epub 2011 Mar 8.
Treatment of bifurcation lesions with the Tryton Sidebranch stent has been shown to be feasible with an acceptable clinical outcome and low side branch late loss in the first in man trial.
To report acute procedural and six month clinical follow-up after the use of the Tryton Sidebranch stent in an "all comer" registry.
The first 100 coronary bifurcation lesions assigned for treatment with the Tryton stent were included in a prospective registry. Procedural and angiographic success rates were determined from patient charts and pre- and postprocedural quantitative coronary angiography.
Totally, 96 patients with 100 lesions were included in the study. Seventy-two percent presented with stable angina, 25% with unstable angina/NSTEMI, and 3% STEMI. The bifurcation was located in the left main in 8%. Two lesions were chronic total occlusions. Sixty-nine percent were true bifurcation lesions. One failure of stent delivery occurred. Acute gain in SB was 0.76 ± 0.64 mm and three patients had residual stenosis of >30%. Angiographic success rate was 95%; procedural success rate reached 94%. Peri-procedural MI occurred in two and there was one cardiac death during hospitalization. At a median six months follow-up, TLR rate was 4%, MI 3%, and cardiac death 1%. The percentage MACE-free survival at six months was 94%. No cases of definite stent thrombosis occurred.
In a real world the use of the Tryton Sidebranch stent is associated with good procedural safety and angiographic success rate and acceptable outcome at six months of follow-up.
在首例人体试验中，使用 Tryton Sidebranch 支架治疗分叉病变具有可行性，且临床结果可接受，分支晚期丢失率低。
报告在“所有患者”注册研究中使用 Tryton Sidebranch 支架的急性手术过程和 6 个月临床随访结果。
将 100 例拟行 Tryton 支架治疗的冠状动脉分叉病变患者纳入前瞻性注册研究。通过患者病历和术前、术后定量冠状动脉造影术确定手术成功率和血管造影成功率。
共纳入 96 例患者的 100 处病变。72%的患者表现为稳定型心绞痛，25%的患者表现为不稳定型心绞痛/NSTEMI，3%的患者表现为 STEMI。分叉位于左主干 8%。2 处病变为慢性完全闭塞。69%为真性分叉病变。有 1 例支架输送失败。SB 的急性获得为 0.76±0.64mm，3 例患者存在残余狭窄>30%。血管造影成功率为 95%；手术成功率达到 94%。围手术期心肌梗死发生 2 例，住院期间发生心脏性死亡 1 例。中位 6 个月随访时，TLR 发生率为 4%，心肌梗死发生率为 3%，心脏性死亡率为 1%。6 个月时无主要不良心脏事件生存率为 94%。无明确支架血栓形成病例。
在真实世界中，使用 Tryton Sidebranch 支架治疗分叉病变具有良好的手术安全性和血管造影成功率，6 个月随访结果可接受。
