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全生命周期多样性社区的健康老龄化 (HANDLS):克服实施一项关于健康、种族和社会经济地位的纵向、流行病学、城市研究的障碍。

Healthy aging in neighborhoods of diversity across the life span (HANDLS): overcoming barriers to implementing a longitudinal, epidemiologic, urban study of health, race, and socioeconomic status.

机构信息

National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, MD 21224-2816, USA.

出版信息

Ethn Dis. 2010 Summer;20(3):267-75.

PMID:20828101
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3040595/
Abstract

OBJECTIVE

Examine the influences of race, socioeconomic status, sex, and age on barriers to participation in a study of cross-sectional differences and longitudinal changes in health-related outcomes.

METHODS

We designed a multidisciplinary, community-based, prospective longitudinal epidemiologic study among socioeconomically diverse African Americans and Whites. We recruited 3722 participants from Baltimore, Md. with a mean age of 47.7 (range 30-64) years, 45% males; 2200 African Americans (59%) and 1522 whites (41%); 41% reported household incomes below the 125% poverty delimiter.

RESULTS

There were no significant age differences associated with sex or race. Participants below the 125% poverty delimiter were slightly younger than those above the delimiter. Age, race, and sex, but not poverty status, were associated with the likelihood of a physical examination. Older participants, women, and Whites were more likely to complete their examinations. Among those who completed their examinations, there were no age differences associated with sex and poverty status, but African Americans were negligibly younger than Whites.

CONCLUSIONS

Although some literature suggests that minorities and low-income people are less willing to participate in clinical research, these baseline data suggest that African Americans individuals and individuals from households with incomes below 125% of the poverty level are at least as willing to participate in observational clinical studies as Whites and higher income individuals of similar age and sex.

摘要

目的

探讨种族、社会经济地位、性别和年龄对参与横断面差异和健康相关结局纵向变化研究的障碍的影响。

方法

我们设计了一项多学科、以社区为基础的前瞻性纵向流行病学研究,研究对象为社会经济地位不同的非裔美国人和白人。我们从马里兰州巴尔的摩招募了 3722 名参与者,平均年龄为 47.7 岁(范围为 30-64 岁),其中 45%为男性;2200 名非裔美国人(59%)和 1522 名白人(41%);41%的家庭收入低于贫困线的 125%。

结果

性别或种族与年龄无显著差异。低于贫困线 125%的参与者比高于贫困线的参与者略年轻。年龄、种族和性别,但不是贫困状况,与体格检查的可能性相关。年龄较大的参与者、女性和白人更有可能完成检查。在完成检查的参与者中,性别和贫困状况与年龄无差异,但非裔美国人比白人略年轻。

结论

尽管一些文献表明少数民族和低收入人群参与临床研究的意愿较低,但这些基线数据表明,非裔美国人和收入低于贫困线 125%的家庭的个人至少与年龄和性别相似的白人及高收入人群一样愿意参与观察性临床研究。

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Barriers to recruiting underrepresented populations to cancer clinical trials: a systematic review.招募代表性不足人群参与癌症临床试验的障碍:一项系统综述。
Cancer. 2008 Jan 15;112(2):228-42. doi: 10.1002/cncr.23157.
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