度洛西汀治疗纤维肌痛。
Duloxetine for the treatment of fibromyalgia.
机构信息
Oregon Health and Science University, School of Nursing, Portland, OR 97239, USA.
出版信息
Expert Rev Clin Immunol. 2010 Sep;6(5):745-56. doi: 10.1586/eci.10.64.
Abstract
This article presents a brief review of the physiologic abnormalities seen in fibromyalgia, current theories of widespread pain, and treatment options, including emerging therapeutics, with a focus on the use of duloxetine to manage fibromyalgia symptoms. Major clinical trials that examine the efficacy and effectiveness of duloxetine to date are reviewed, and safety issues are discussed.
摘要
本文简要回顾了纤维肌痛中观察到的生理异常、目前的广泛疼痛理论以及治疗选择，包括新兴疗法，并重点介绍了度洛西汀治疗纤维肌痛症状的应用。本文回顾了迄今为止评估度洛西汀疗效和有效性的主要临床试验，并讨论了安全性问题。
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