Barabash R D, Levitskiĭ A R
Vopr Med Khim. 1978 May-Jun;24(3):291-310.
Data on the role of oral lysozyme, ribonuclease, deoxyribonuclease and peroxidase in antimicrobial defense of the macroorganism are reviewed. The biochemical and physiological properties of the enzymes secreted by salivary glands and released from emigrating leukocytes are discussed. Spectra of antimicrobial action of the enzymes and participation of these enzymes in maintaining the stability of oral biocenosis are described as well as the regulation of these enzymatic activities and the pathogenetic significance of impairments in their secretion. The most perspective aspects of the problems discussed are outlined for further investigation.
本文综述了关于口服溶菌酶、核糖核酸酶、脱氧核糖核酸酶和过氧化物酶在机体抗菌防御中作用的数据。讨论了唾液腺分泌的以及从迁移的白细胞中释放的这些酶的生化和生理特性。描述了这些酶的抗菌作用谱及其在维持口腔生物群落稳定性中的作用，以及这些酶活性的调节及其分泌受损的致病意义。概述了所讨论问题中最具前景的方面以供进一步研究。
