Department of Neurology & Psychiatry, School of Medicine, Saint Louis University, St. Louis, Missouri 63104, USA.
J Am Geriatr Soc. 2010 Oct;58(10):1941-5. doi: 10.1111/j.1532-5415.2010.03057.x. Epub 2010 Sep 9.
To investigate associations between quality of life (QoL) and incontinence in a population-based African-American sample.
Cross-sectional survey.
Metropolitan St. Louis, Missouri.
Eight hundred fifty-three non-institutionalized African Americans aged 52 to 68 in the African American Health study.
Respondents who reported having involuntarily lost urine over the previous month were classified as having urinary incontinence (UI), and respondents who reported having lost control of their bowels or stool over the past year were classified as having fecal incontinence (FI). QoL was measured using the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) and the 11-item Center for Epidemiologic Studies Depression Scale (CES-D).
Prevalences of UI and FI were 12.1% (weighted n=102/841) and 5.0% (weighted n=42/841). Participants with UI and those with FI had worse SF-36 scores than their referent groups (physical function -15.5 and -38.1 points, respectively; role physical -13.2 and -26.5 points; bodily pain -15.7 and -24.5 points; general health perceptions -15.5 and -27.6 points; vitality -15.0 and -16.5 points; social functioning -18.4 and -25.6 points; role emotional -13.2 and -22.1 points; mental health -12.2 and -17.5 points; all Ps<.001), adjusting for age, sex, body mass index, and chronic conditions. Proportions with clinically relevant levels of depressive symptoms were also higher in both groups (UI+17.9%; P<.001) and FI (+37.2%; P<.001) than in their referent groups.
UI and FI were strongly associated with worse health-related QoL as well as symptoms of depression in this population-based sample of African Americans.
调查生命质量（QoL）与非裔美国人样本中失禁之间的关联。
横断面调查。
密苏里州圣路易斯都会区。
非裔美国人健康研究中年龄在 52 至 68 岁之间的 853 名非住院的非裔美国人。
报告在过去一个月内非自愿失去尿液的受访者被归类为患有尿失禁（UI），报告在过去一年中失去对肠道或粪便控制的受访者被归类为患有粪便失禁（FI）。使用医疗结果研究 36 项简明健康调查问卷（SF-36）和 11 项流行病学研究中心抑郁量表（CES-D）来测量 QoL。
UI 和 FI 的患病率分别为 12.1%（加权 n=102/841）和 5.0%（加权 n=42/841）。UI 组和 FI 组的 SF-36 评分均低于参照组（生理功能分别下降 15.5 和 -38.1 分；生理职能分别下降 13.2 和 -26.5 分；躯体疼痛分别下降 15.7 和 -24.5 分；总体健康感分别下降 15.5 和 -27.6 分；活力分别下降 15.0 和 -16.5 分；社会功能分别下降 18.4 和 -25.6 分；情感职能分别下降 13.2 和 -22.1 分；心理健康分别下降 12.2 和 -17.5 分；所有 P 值均<.001），调整了年龄、性别、体重指数和慢性疾病。两个组中具有临床相关抑郁症状的比例也更高（UI 组为 17.9%；P<.001），FI 组为 37.2%（P<.001），高于参照组。
在这个基于人群的非裔美国人样本中，UI 和 FI 与健康相关 QoL 更差以及抑郁症状明显相关。
