Fridenshteĭn A Ia, Latsinik N V, Gorskaia Iu F, Luriia E A
Biull Eksp Biol Med. 1990 Nov;110(11):509-10.
In 24 hours adherent marrow cell cultures (AMCC) were represented by single stretched fibroblasts. In non-feeder-supplemented AMCC most of the CFU-f remained single fibroblasts or passed through 1-3 cell doublings [correction of dudlings]. The colony stimulating activity of irradiated marrow cells was found to be diffuse across the Millipore filter, which seems to indicate that haemopoietic marrow cells produce a colony stimulating factor which is required for triggering the CFU-f from the Go-period of the cell cycle into cell proliferation.
在24小时的贴壁骨髓细胞培养（AMCC）中，可见单个伸展的成纤维细胞。在无饲养层补充的AMCC中，大多数集落形成单位 - 成纤维细胞（CFU - f）仍为单个成纤维细胞，或经历1 - 3次细胞倍增[将dudlings校正为doublings]。发现经辐照的骨髓细胞的集落刺激活性可扩散穿过微孔滤膜，这似乎表明造血骨髓细胞产生一种集落刺激因子，该因子是触发CFU - f从细胞周期的G0期进入细胞增殖所必需的。
