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胫骨高位截骨术治疗膝关节内侧间室骨关节炎的长期生存率。

Long-term survival of high tibial osteotomy for medial compartment osteoarthritis of the knee.

机构信息

North Sydney Orthopaedic & Sports Medicine Centre, Sydney, Australia.

出版信息

Am J Sports Med. 2011 Jan;39(1):64-70. doi: 10.1177/0363546510377445. Epub 2010 Sep 10.

Abstract

BACKGROUND

The management of degenerative arthritis of the knee in the younger, active patient presents a challenge to the orthopaedic surgeon. Surgical treatment options include high tibial osteotomy (HTO), unicompartmental knee arthroplasty, and total knee arthroplasty.

PURPOSE

To examine the long-term survival of closing wedge HTO in a large series of patients up to 19 years after surgery.

STUDY DESIGN

Case series; Level of evidence, 4.

METHODS

Four hundred fifty-five consecutive patients underwent lateral closing wedge HTO for medial compartment osteoarthritis between 1990 and 2001. Between 2008 and 2009, patients were contacted via telephone, and assessment included incidence of further surgery, current body mass index (BMI), Oxford Knee Score, and British Orthopaedic Association Patient Satisfaction Scale. Failure was defined as the need for revision HTO or conversion to unicompartmental knee arthroplasty or total knee arthroplasty. Survival analysis was completed using the Kaplan-Meier method.

RESULTS

High tibial osteotomy survival was determined in 413 patients (91%). Of the 397 remaining living patients at the time of final review, 394 (99%) were contacted for follow-up via telephone interview. The probability of survival for HTO at 5, 10, and 15 years was 95%, 79%, and 56%, respectively. Multivariate regression analysis showed that age under 50 years (P = .001), BMI less than 25 (P = .006), and ACL deficiency (P = .03) were associated with better odds of survival. Mean Oxford Knee Score was 40 of 48 (range, 17-48). Overall, 85% of patients were enthusiastic or satisfied, and 84% would undergo HTO again at a mean 12 years of follow-up.

CONCLUSION

High tibial osteotomy can be effective for periods longer than 15 years; however, results do deteriorate over time. Age less than 50 years, normal BMI, and ACL deficiency were independent factors associated with improved long-term survival of HTO.

摘要

背景

对于年轻、活跃的膝关节退行性关节炎患者,骨科医生面临着挑战。手术治疗方案包括胫骨高位截骨术(HTO)、单髁膝关节置换术和全膝关节置换术。

目的

在一项长达 19 年的随访中,检查大量患者中闭合楔形 HTO 的长期存活率。

研究设计

病例系列;证据水平,4 级。

方法

1990 年至 2001 年期间,455 例连续患者接受了外侧闭合楔形 HTO 治疗内侧间室骨关节炎。2008 年至 2009 年,通过电话联系患者,评估包括进一步手术的发生率、当前体重指数(BMI)、牛津膝关节评分和英国矫形协会患者满意度量表。失败定义为需要进行翻修 HTO 或转换为单髁膝关节置换术或全膝关节置换术。使用 Kaplan-Meier 方法进行生存分析。

结果

413 例(91%)患者确定了 HTO 生存率。在最终复查时,397 例仍存活的患者中,有 394 例(99%)通过电话访谈进行了随访。HTO 在 5、10 和 15 年的生存率分别为 95%、79%和 56%。多变量回归分析显示,50 岁以下年龄(P=.001)、BMI 小于 25(P=.006)和 ACL 缺陷(P=.03)与更好的生存几率相关。平均牛津膝关节评分 48 分(范围,17-48 分)。总体而言,85%的患者热情或满意,84%的患者在平均 12 年的随访后会再次接受 HTO。

结论

HTO 可有效使用 15 年以上;然而,结果会随着时间的推移而恶化。年龄小于 50 岁、正常 BMI 和 ACL 缺陷是与 HTO 长期生存改善相关的独立因素。

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