Department of Chemistry and Biochemistry, City University of New York - Hunter College, New York, NY 10065, USA.
Nanoscale. 2010 Nov;2(11):2373-6. doi: 10.1039/c0nr00457j. Epub 2010 Sep 13.
Pb-binding TAR-1 peptides (Ile-Ser-Leu-Leu-His-Ser-Thr) were covalently conjugated on a bolaamphiphile peptide nanotube substrate and the precursors of PbSe were incubated at room temperature. This resulted in the growth of highly crystalline PbSe nanocubes on this biomimetic cylindrical substrate. The growth mechanism to generate nanocubes occurs via the directed self-assembly of nanoparticles and then nanoparticle fusion. The peptide conformation and the cylindrical peptide nanotube substrate play important roles in the mesoscopic crystallization of PbSe nanocubes. Changing the buffer for the peptide immobilization process from 2-(N-morpholino)ethanesulfonic acid to phosphate induces a transformation in the nanocrystal shape from nanocube to nanorods. The conformational change of the TAR-1 peptide on the nanotubes due to the change in the buffer seems to be responsible for aggregating intermediate nanoparticles in different directions for the directed fusion and mesoscopic crystallization of PbSe into the different shapes.
Pb 结合 TAR-1 肽（Ile-Ser-Leu-Leu-His-Ser-Thr）通过共价键连接在 bolaamphiphile 肽纳米管基底上，然后在室温下孵育 PbSe 的前体。这导致高度结晶的 PbSe 纳米立方体在这种仿生圆柱形基底上生长。生成纳米立方体的生长机制是通过纳米颗粒的定向自组装，然后是纳米颗粒的融合。肽构象和圆柱形肽纳米管基底在 PbSe 纳米立方体的介观结晶中起着重要作用。将肽固定化过程中的缓冲液从 2-（N-吗啉代）乙磺酸变为磷酸盐，会导致纳米晶体的形状从纳米立方体转变为纳米棒。由于缓冲液的变化，纳米管上 TAR-1 肽的构象变化似乎负责将中间纳米颗粒在不同方向聚集，以便将 PbSe 定向融合和介观结晶成不同的形状。
