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恰加斯病:阿根廷查科省新庞贝使命的 Wichi 和克里奥尔社区的血清学和心电图研究。

Chagas disease: serological and electrocardiographic studies in Wichi and Creole communities of Misión Nueva Pompeya, Chaco, Argentina.

机构信息

Facultad de Ciencias Médicas, Universidad Nacional de Córdoba and Coordinación Nacional de Control de Vectores, Córdoba, Argentina.

出版信息

Mem Inst Oswaldo Cruz. 2010 Aug;105(5):621-7. doi: 10.1590/s0074-02762010000500004.

DOI:10.1590/s0074-02762010000500004
PMID:20835607
Abstract

Chagas disease, which is caused by Trypanosoma cruzi, affects nearly 16 million people in Latin America and causes 75-90 million people to be at risk of infection. The disease is urbanizing and globalizing due to frequent migrations. There are regions of high prevalence of infection, including the north-eastern provinces of Argentina and the entire phytogeographic region known as the Gran Chaco. In the province of Chaco, Argentina, there are places inhabited by native populations such as the Wichi and Toba communities, among others. Many Creole populations resulting from miscegenation with European colonists and immigrants coexist within these communities. It has been widely accepted that in the chronic phase of the disease, between 25-30% of individuals develop some form of cardiac disease, with the right bundle-branch block being the most typical condition described so far. The aim of this work was to study the prevalence of Chagas infection and its electrocardiographic profile in the Wichi and Creole populations of Misión Nueva Pompeya, in the area known as Monte Impenetrable in Chaco, to determine the prevalence and the pattern of heart diseases produced by Chagas disease in this region.

摘要

恰加斯病由克氏锥虫引起,影响拉丁美洲近 1600 万人,并使 7500 万至 9000 万人面临感染风险。由于频繁的迁徙,这种疾病正在向城市和全球化发展。存在着高感染率的地区,包括阿根廷东北部省份和被称为大查科的整个植物地理区域。在阿根廷的查科省,有一些地方居住着土著居民,如维奇和托巴社区等。许多克里奥尔人是欧洲殖民者和移民与当地居民混血的结果,他们与这些社区共存。人们普遍认为,在疾病的慢性期,25-30%的个体会出现某种形式的心脏病,右束支传导阻滞是迄今为止描述的最典型的情况。这项工作的目的是研究恰加斯病在查科省蒙特因佩特里内地区的新庞贝使命的维奇和克里奥尔人群中的感染流行情况及其心电图特征,以确定该地区恰加斯病引起的心脏病的流行率和模式。

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