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High levels of human infection with Trypanosoma cruzi associated with the domestic density of infected vectors and hosts in a rural area of northeastern Argentina.高人体感染克氏锥虫水平与阿根廷东北部农村地区感染媒介和宿主的家庭密度有关。
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Higher congenital transmission rate of Trypanosoma cruzi associated with family history of congenital transmission.先天性传播率较高与先天性传播的家族史有关。
Rev Soc Bras Med Trop. 2020;53:e20190560. doi: 10.1590/0037-8682-0560-2019. Epub 2020 Apr 27.
2
[Congenital transmission of Trypanosoma cruzi. Argentina 2002-2014].[克氏锥虫的先天性传播。阿根廷，2002年至2014年]
Medicina (B Aires). 2019;79(2):81-89.
3
Inequalities in the social determinants of health and Chagas disease transmission risk in indigenous and creole households in the Argentine Chaco.社会决定因素不平等与阿根廷查科地区土著和克里奥尔人家庭中恰加斯病传播风险。
Parasit Vectors. 2019 Apr 27;12(1):184. doi: 10.1186/s13071-019-3444-5.
4
[Seroprevalence of Chagas´Disease in older than 14 years old in rural Chaco areas of Santa Fe Province.].[圣达菲省查科农村地区14岁以上人群恰加斯病血清阳性率]
Rev Fac Cien Med Univ Nac Cordoba. 2019 Feb 27;76(1):47-51. doi: 10.31053/1853.0605.v76.n1.21946.
5
Congenital Chagas disease: alert of research negligence.先天性恰加斯病：研究疏忽的警示
Rev Soc Bras Med Trop. 2019 Feb 21;52:e20180069. doi: 10.1590/0037-8682-0069-2018.
6
Factors associated with the presence of triatomines in rural areas of south Argentine Chaco.阿根廷查科省南部农村地区存在锥蝽的相关因素。
Rev Soc Bras Med Trop. 2019 Jan 14;52:e20180357. doi: 10.1590/0037-8682-0357-2018.
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Chagas disease.恰加斯病。
Lancet. 2018 Jan 6;391(10115):82-94. doi: 10.1016/S0140-6736(17)31612-4. Epub 2017 Jun 30.
8
Treatment of Infected Women of Childbearing Age Prevents Congenital Trypanosoma cruzi Infection by Eliminating the Parasitemia Detected by PCR.治疗育龄期感染妇女可消除 PCR 检测到的寄生虫血症，从而预防先天性克氏锥虫感染。
J Infect Dis. 2017 May 1;215(9):1452-1458. doi: 10.1093/infdis/jix087.
9
Chagas' disease in Aboriginal and Creole communities from the Gran Chaco Region of Argentina: Seroprevalence and molecular parasitological characterization.阿根廷大查科地区原住民和克里奥尔人社区的恰加斯病：血清阳性率及分子寄生虫学特征
Infect Genet Evol. 2016 Jul;41:84-92. doi: 10.1016/j.meegid.2016.03.028. Epub 2016 Apr 4.
10
[Not Available].[无可用内容]
Salud Publica Mex. 2016 Jan-Feb;58(1):3-4.

格兰查科南部城乡土著人群中查加斯病的血清流行率。

Seroprevalence of Chagas disease in urban and rural indigenous populations of the south of Gran Chaco.

机构信息

Universidad Nacional del Litoral, Facultad de Bioquímica y Ciencias Biológicas, Centro de Investigaciones sobre Endemias Nacionales. Santa Fe, Argentina.

Ministerio de Salud de la Provincia de Santa Fe, Hospital Central de Reconquista. Reconquista, Argentina.

出版信息

Rev Soc Bras Med Trop. 2022 Apr 29;55:e04792021. doi: 10.1590/0037-8682-0479-2021. eCollection 2022.

DOI:10.1590/0037-8682-0479-2021
PMID:35522808
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9070071/
Abstract

BACKGROUND

In Latin America, Chagas disease is endemic, with a high prevalence in rural indigenous communities and an increasing prevalence in urban areas owing to migration from rural areas with active vector transmission. This study aimed to assess differences in the prevalence of Chagas disease in urban and rural moqoit communities, one of the main ethnic indigenous groups in the south of Gran Chaco.

METHODS

A seroprevalence study was conducted in six moqoit populations in the Santa Fe province, Argentina. The variables studied were serology results for Chagas disease, residents of urban or rural areas, age, and sex.

RESULTS

The results showed that 9.26% of the 702 volunteers evaluated and 18.32% of the 131women of childbearing potential were seropositive. According to the calculated prevalence ratio, the prevalence of Chagas disease in urban communities was6.41 (95% confidence inverval: 3.73-11.02) times higher than that in rural communities: 21.59% in urban communities vs. 3.37%in rural communities.

CONCLUSIONS

The seroprevalence found in the moqoit community was higher than the estimated level for the general population of the same region, with a greater impact in urban areas than in rural areas. The urbanization of groups of people with poor socio-sanitary conditions in the second half of the 20th century could have caused this higher seroprevalence of Chagas disease.

摘要

背景

在拉丁美洲，恰加斯病流行，在农村土著社区中发病率较高，由于农村地区向城市的移民导致该病在城市地区的发病率也在上升，而这些农村地区正是有传播媒介的活动地区。本研究旨在评估恰加斯病在格兰查科南部的主要土著民族之一莫奎特社区的城乡差异。

方法

在阿根廷圣达菲省的六个莫奎特社区进行了血清流行率研究。研究的变量包括恰加斯病血清学结果、居住在城市或农村地区、年龄和性别。

结果

结果显示，702 名评估志愿者中有 9.26%，131 名育龄妇女中有 18.32%呈血清阳性。根据计算出的患病率比，城市社区的恰加斯病患病率是农村社区的 6.41 倍（95%置信区间：3.73-11.02）：城市社区为 21.59%，农村社区为 3.37%。

结论

莫奎特社区发现的血清阳性率高于同一地区一般人群的估计水平，城市地区的影响大于农村地区。20 世纪下半叶，社会卫生条件较差的人群城市化可能导致了更高的恰加斯病血清阳性率。