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两种不同物理治疗技术的长期对比试验;体位引流加叩击与自主引流在囊性纤维化治疗中的应用。

Long-term comparative trial of two different physiotherapy techniques; postural drainage with percussion and autogenic drainage, in the treatment of cystic fibrosis.

机构信息

Cystic Fibrosis Clinic, BC's Children's Hospital, Vancouver, BC, Canada.

出版信息

Pediatr Pulmonol. 2010 Nov;45(11):1064-9. doi: 10.1002/ppul.21247.

Abstract

UNLABELLED

In N. America, over the past decade, various airway clearance techniques (ACT) have been introduced for the treatment of cystic fibrosis (CF). We hypothesized that autogenic drainage (AD), an ACT developed in Belgium would be as effective as postural drainage with percussion (PD) in treating patients with CF.

METHODS

Thirty-six CF patients, aged 12-18 years, with Shwachman score 65-98, were enrolled in a 2-year cross-over trial. Patients were matched as pairs and members of each pair were randomly assigned to two groups. For the first study year, Group A performed PD while Group B performed AD. At the end of 1 year Groups A and B crossed over physiotherapy techniques. Clinical status and pulmonary function (FVC, FEV(1), FEF(25-75)) were measured at 3 monthly intervals. Only results from the first year of the study are reported, as 10 out of 17 patients who had completed performing AD for the first year refused to change back to PD for the second year.

RESULTS

During the first year of the study, both the AD and PD groups demonstrated improved pulmonary function with no significant difference between the two groups. Change in FVC and FEV(1) percent predicted for Groups A and B was 0.47 ± 1.65(se) versus 2.35 ± 1.51(se) and 2.09 ± 2.2(se) versus 0.92 ± 2.25(se). However, CF patients exhibited a marked preference for the AD technique. Results suggest that both AD and PD are effective methods of performing physiotherapy for CF patients and that the benefits of either technique are enhanced by measures which encourage adherence.

摘要

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在过去的十年中,北美地区引入了各种气道清除技术(ACT)来治疗囊性纤维化(CF)。我们假设,在比利时开发的自主引流(AD)作为一种 ACT,其在治疗 CF 患者方面的效果与体位引流加叩击(PD)一样有效。

方法

36 名年龄在 12-18 岁之间、Shwachman 评分在 65-98 分的 CF 患者参加了一项为期 2 年的交叉试验。患者按对匹配,并将每对中的成员随机分配到两组。在第一年研究中,A 组进行 PD,B 组进行 AD。在第 1 年末,A 组和 B 组交叉进行物理治疗。每 3 个月测量一次临床状况和肺功能(FVC、FEV1、FEF25-75)。仅报告研究第一年的结果,因为第一年完成 AD 治疗的 17 名患者中有 10 名拒绝在第二年恢复 PD。

结果

在研究的第一年,AD 和 PD 两组的肺功能都有所改善,但两组之间没有显著差异。A 组和 B 组的 FVC 和 FEV1 预计百分比变化分别为 0.47 ± 1.65(se)对 2.35 ± 1.51(se)和 2.09 ± 2.2(se)对 0.92 ± 2.25(se)。然而,CF 患者对 AD 技术表现出明显的偏好。结果表明,AD 和 PD 都是治疗 CF 患者的有效物理治疗方法,通过鼓励坚持的措施,任何一种技术的益处都可以得到增强。

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