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Helicobacter pylori infection.

作者信息

Graham David Y, Fischbach Lori

出版信息

N Engl J Med. 2010 Aug 5;363(6):595-6; author reply 596. doi: 10.1056/NEJMc1006158.

DOI:10.1056/NEJMc1006158
PMID:20836243
Abstract
摘要

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Helicobacter pylori infection.幽门螺杆菌感染
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The best and worst treatments for Helicobacter pylori.幽门螺杆菌的最佳和最差治疗方法。
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[What is currently the Helicobacter pylori eradication therapy of choice? Triple therapy (PPI, amoxicillin and clarithromycin) or sequential therapy (PPI and amoxicillin for 5 days followed by PPI, clarithromycin and metronidazole for a further 5 days)?].目前幽门螺杆菌根除治疗的首选方案是什么？三联疗法（质子泵抑制剂、阿莫西林和克拉霉素）还是序贯疗法（质子泵抑制剂和阿莫西林连用5天，随后质子泵抑制剂、克拉霉素和甲硝唑再连用5天）？
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Bismuth, lansoprazole, amoxicillin and metronidazole or clarithromycin as first-line Helicobacter pylori therapy.铋剂、兰索拉唑、阿莫西林和甲硝唑或克拉霉素作为一线幽门螺杆菌治疗。
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Empiric use of standard triple therapy in eradication does not require readjustment in the clarithromycin resistance cut-off point.在根除治疗中经验性使用标准三联疗法时，无需调整克拉霉素耐药临界值。
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Personalized Approach in Eradication of Infection.根除感染的个性化方法。
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Helicobacter pylori-Induced DNA Damage Is a Potential Driver for Human Gastric Cancer AGS Cells.
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Rescue Therapy with a Proton Pump Inhibitor Plus Amoxicillin and Rifabutin for Helicobacter pylori Infection: A Systematic Review and Meta-Analysis.质子泵抑制剂联合阿莫西林和利福布汀用于幽门螺杆菌感染的挽救治疗：一项系统评价和荟萃分析
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High Prevalence of Helicobacter pylori hopQ II Genotype Isolated from Iranian Patients with Gastroduodenal Disorders.从患有胃十二指肠疾病的伊朗患者中分离出的幽门螺杆菌hopQ II基因型的高流行率。
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