FAMIREA Group Study, Saint Louis Teaching Hospital, Medical Intensive Care Unit and Biostatistics Department, Paris 7 University, Assistance Publique-Hopitaux de Paris, France.
J Palliat Med. 2010 Sep;13(9):1131-7. doi: 10.1089/jpm.2010.0109.
The intensive care unit (ICU) experience has been reported to cause adverse health effects in families during and after the ICU stay. The objective of this study was to evaluate health-related quality of life (HRQOL) in relatives of patients 90 days after ICU discharge or death.
Multicenter observational study.
Twenty-one ICUs in France.
Among 459 eligible relatives of ICU patients, 284 (62%) were included in the study.
None.
During a telephone interview, the SF-36 was completed to assess HRQOL 90 days after ICU discharge or death. The physical component summary score of the SF-36 was normal (89/100 [66-94]) but the mental component summary score showed substantial impairments (emotional role, 67 [50-80]; social functioning, 70 [60-90]; vitality, 60 [45-70]; and mental health, 60 [48-2]). Moreover, 35.9% of relatives were taking anxiolytic or antidepressant drugs, and 8.4% were taking psychotropic agents prescribed since the discharge or death of the patient. Among factors independently associated with a worse mental score, 2 were patient-related (admission for shock or implementation of end-of-life decision), 6 were family-related (older age, female gender, child of the patient, low income, chronic disease, and newly prescribed psychotropic medications), and 1 was related to the ICU experience (perceived conflicts between ICU staff and relatives).
The SF-36 showed evidence of impaired mental health in relatives of ICU patients 90 days after discharge. Better end-of-life care, psychiatric support after the ICU experience, and better conflict prevention and resolution are potential targets for improvement.
据报道，重症监护病房（ICU）的经历会在 ICU 住院期间和之后对患者家属的健康产生不良影响。本研究的目的是评估 ICU 出院或死亡 90 天后患者家属的健康相关生活质量（HRQOL）。
多中心观察性研究。
法国的 21 个 ICU。
在 459 名符合条件的 ICU 患者家属中，有 284 名（62%）参与了研究。
无。
通过电话访谈，使用 SF-36 评估 ICU 出院或死亡 90 天后的 HRQOL。SF-36 的生理成分综合评分正常（89/100 [66-94]），但心理成分综合评分显示出明显的损伤（情绪角色，67 [50-80]；社会功能，70 [60-90]；活力，60 [45-70]；心理健康，60 [48-2]）。此外，35.9%的家属正在服用抗焦虑药或抗抑郁药，8.4%的家属在患者出院或死亡后正在服用精神药物。与较差的心理评分相关的独立因素包括 2 个与患者相关的因素（休克入院或实施临终决策）、6 个与家庭相关的因素（年龄较大、女性、患者的子女、低收入、慢性疾病和新处方的精神药物）和 1 个与 ICU 经历相关的因素（ICU 工作人员与家属之间的感知冲突）。
SF-36 显示 ICU 患者家属出院后 90 天心理健康受损的证据。更好的临终关怀、ICU 体验后的精神支持，以及更好地预防和解决冲突，可能是需要改进的目标。
