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超声造影在钝性肝外伤中的应用:动物实验。

Contrast-enhanced ultrasound for blunt hepatic trauma: an animal experiment.

机构信息

Department of Ultrasound, Liuhuaqiao Hospital, Guangzhou 510010, China.

出版信息

Am J Emerg Med. 2010 Sep;28(7):828-33. doi: 10.1016/j.ajem.2009.07.028. Epub 2010 Jan 28.

DOI:10.1016/j.ajem.2009.07.028
PMID:20837263
Abstract

OBJECTIVE

The aim of this study was to study the value of contrast-enhanced ultrasound (CEUS) in the diagnosis of active hemorrhage and intraparenchymal lesions in blunt hepatic trauma versus conventional ultrasound (US).

METHODS

Twenty heparinized and anesthetized domestic pigs have been created to animal models with blunt hepatic trauma by a special impacting device. Conventional US and CEUS were performed to determine if hepatic traumas were present.

RESULTS

Active hemorrhage, the presence of intraparenchymal lesions, and sonographic pattern were evaluated for conventional US and CEUS, as compared with laparotomy and pathologic findings. Contrast-enhanced US detected active hemorrhage from the injured livers in all cases, but conventional US did not find that in any case. The sensitivity of CEUS and conventional US in diagnosing intraparenchymal lesions of blunt hepatic trauma were 100% and 60%, respectively.

CONCLUSIONS

Contrast-enhanced US is more sensitive than conventional US in determining the active hemorrhage and intraparenchymal lesions in blunt hepatic trauma.

摘要

目的

本研究旨在探讨超声造影(CEUS)在诊断钝性肝外伤中的活性出血和实质内病变方面的价值,并与常规超声(US)进行比较。

方法

采用特殊的撞击装置,对 20 只肝素化麻醉的家猪进行钝性肝外伤动物模型的制作。对肝脏外伤进行常规 US 和 CEUS 检查,以确定是否存在肝外伤。

结果

将常规 US 和 CEUS 检查的活性出血、实质内病变和超声表现与剖腹探查和病理结果进行比较。CEUS 检测到所有损伤肝脏的活性出血,但常规 US 未发现任何一例。CEUS 和常规 US 诊断钝性肝外伤实质内病变的灵敏度分别为 100%和 60%。

结论

CEUS 在确定钝性肝外伤的活性出血和实质内病变方面比常规 US 更敏感。

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Effectiveness of contrast-enhanced ultrasound and serum liver enzyme measurement in detection and classification of blunt liver trauma.超声造影和血清肝酶检测在钝性肝外伤检测与分级中的有效性
J Int Med Res. 2017 Feb;45(1):170-181. doi: 10.1177/0300060516678525. Epub 2017 Jan 11.
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A novel hemostatic sealant composed of gelatin, transglutaminase and thrombin effectively controls liver trauma-induced bleeding in dogs.
一种新型的止血密封剂由明胶、转谷氨酰胺酶和凝血酶组成,可有效控制犬肝脏创伤引起的出血。
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