Department of Dermatology, Maastricht University Medical Centre, Maastricht, The Netherlands.
J Eur Acad Dermatol Venereol. 2011 May;25(5):565-9. doi: 10.1111/j.1468-3083.2010.03839.x. Epub 2010 Sep 14.
As a result of the high prevalence, basal cell carcinoma (BCC) causes a significant and expensive health care problem.
In this study, we evaluate the proportional increase in BCC by histological subtype over the last two decades.
We retrospectively reviewed all primary histological confirmed BCCs diagnosed in the Maastricht University Medical Centre in The Netherlands in the years 1991, 1999 and 2007.
An annual increase of the number of BCCs of 7% for both genders was shown. The age-standardized incidence rates for BCC increased between 1991 and 2007 from 54.2 to 162.1 per 100, 000 men and from 61.7 to 189.8 per 100, 000 women. The proportion of superficial BCC increased significantly from 17.6% to 30.7%.
The incidence of BCC is continuing to increase this century. The observed shift to the superficial histological subtype, which can be treated non-surgically, might reduce the workload in the busy dermatologists practice.
基底细胞癌（BCC）的高患病率导致了严重且昂贵的医疗保健问题。
本研究旨在评估过去二十年中 BCC 组织学亚型的比例变化。
我们回顾性分析了 1991 年、1999 年和 2007 年在荷兰马斯特里赫特大学医学中心诊断的所有原发性组织学确诊的 BCC。
显示出两性 BCC 数量的年增长率均为 7%。1991 年至 2007 年间，男性 BCC 的年龄标准化发病率从 54.2/100,000 增加到 162.1/100,000，女性从 61.7/100,000 增加到 189.8/100,000。浅表性 BCC 的比例从 17.6%显著增加到 30.7%。
本世纪 BCC 的发病率仍在持续上升。观察到浅表组织学亚型的转移，这种亚型可以非手术治疗，可能会减少皮肤科医生繁忙工作中的工作量。
