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荷兰原发性基底细胞癌的发病率、患病率和未来趋势。

Incidence, prevalence and future trends of primary basal cell carcinoma in the Netherlands.

机构信息

Department of Dermatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.

出版信息

Acta Derm Venereol. 2011 Jan;91(1):24-30. doi: 10.2340/00015555-1009.

Abstract

Basal cell carcinoma (BCC) incidence rates are increasing worldwide. This study's objective was to estimate the occurrence of BCC in the Netherlands in terms of incidence and prevalence. Data on first primary carcinomas were retrieved from the Eindhoven Cancer Registry and extrapolated to the Dutch population. Extrapolated data showed a total of 444,131, histologically confirmed cases in the Netherlands between 1973 and 2008. During this period, age-adjusted incidence rates (European Standard Population) increased approximately three-fold from 40 to 148 per 100,000 in males and from 34 to 141 in females. Lifetime risk of BCC was 1 in 5-6 for Dutch citizens. Disease prevalence in the Netherlands was 1.4% and almost four times higher than this (5.4%) in the oldest age group (age 65 years or more). Predictions of future trends showed no signs of a plateau in the number of cases. These estimates should urge Dutch policymakers to provide solutions for the growing group of patients with BCC.

摘要

基底细胞癌 (BCC) 的发病率在全球范围内呈上升趋势。本研究旨在根据发病率和患病率来评估荷兰的 BCC 发病情况。从埃因霍温癌症登记处获取了原发性癌症的第一例数据,并将其外推到荷兰人群。外推数据显示,1973 年至 2008 年间,荷兰共有 444,131 例经组织学证实的病例。在此期间,男性的年龄调整发病率(欧洲标准人群)从每 100,000 人 40 例增加到 148 例,女性从每 100,000 人 34 例增加到 141 例。荷兰公民一生中患 BCC 的风险为 1/5-6。荷兰的疾病患病率为 1.4%,而在年龄最大的组(65 岁或以上)中,这一比例几乎高出四倍(5.4%)。对未来趋势的预测显示,病例数量没有出现平稳的迹象。这些估计值应促使荷兰政策制定者为日益增多的 BCC 患者提供解决方案。

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