Nutrition and Public Health Interventions Research Department, Faculty of Epidemiology and Population Health, London, UK.
Contemp Clin Trials. 2011 Jan;32(1):36-9. doi: 10.1016/j.cct.2010.09.002. Epub 2010 Sep 16.
Psychological theory suggests that participants may be more likely to volunteer to join a clinical trial if they perceive places in the trial are a scarce commodity.
We conducted a single blind, randomized controlled trial to test recruitment strategies within the larger txt2stop smoking cessation trial. 1862 people who were eligible for the txt2stop trial but had not yet consented to join were randomized to receive either A) a reminder about the txt2stop trial plus a message that there were only 300 places left, or B) a reminder about the trial only. The outcome was the participant's consent to join the txt2stop trial 3days after messages were sent.
Of 895 participants randomized to the intervention group, 90 (10.1%) had consented to join the txt2stop trial. Of the 967 participants randomized to the control group, 67 (6.9%) had consented to join the txt2stop trial (OR=1.50, 95% CI 1.07-2.12).
Scarcity messages were an effective way to increase recruitment into the txt2stop trial and could be relevant to other trials.
Communicating scarcity is an effective way to increase trial recruitment.
心理学理论表明,如果参与者认为试验中的名额是稀缺的,他们更有可能自愿参加临床试验。
我们进行了一项单盲、随机对照试验,旨在测试更大规模的 txt2stop 戒烟试验中的招募策略。共有 1862 名符合 txt2stop 试验条件但尚未同意参加的人被随机分为两组:A)收到关于 txt2stop 试验的提醒,并收到仅剩 300 个名额的信息;B)仅收到关于试验的提醒。试验结果是参与者在收到信息后 3 天同意参加 txt2stop 试验。
在被随机分配到干预组的 895 名参与者中,有 90 人(10.1%)同意参加 txt2stop 试验。在被随机分配到对照组的 967 名参与者中,有 67 人(6.9%)同意参加 txt2stop 试验(OR=1.50,95%CI 1.07-2.12)。
稀缺信息是增加 txt2stop 试验招募的有效方法,可能对其他试验也有意义。
传达稀缺性是增加试验招募的有效方法。