Perryman L E, McGuire T C, Crawford T B
Am J Vet Res. 1978 Jun;39(6):1043-7.
Sixty-six cases of combined immunodeficiency (CID) in foals were studied to determine the most prevalent causes of infection and death. Lesions of the respiratory system were observed in 59 of the foals and were attributable to infection with equine adenovirus. Pneumocystis carinii, and bacteria. Significant lesions were also observed in liver, pancreas, intestines, heart, and kidneys. Maintenance of foals with CID for experimental purposes is directed at the prevention and control of these secondary infections. Adenovirus can be controlled by administration of horse plasma containing high titers of antiadenovirus antibody. Bacteria are controlled by appropriate antibiotic therapy. Pneumocystis carinii infection remains a significant problem in the maintenance of foals with CID.
对66例马驹联合免疫缺陷（CID）病例进行了研究，以确定感染和死亡的最常见原因。在59匹马驹中观察到呼吸系统病变，这些病变归因于马腺病毒、卡氏肺孢子虫和细菌感染。在肝脏、胰腺、肠道、心脏和肾脏中也观察到明显病变。为实验目的饲养患有CID的马驹旨在预防和控制这些继发感染。腺病毒可通过给予含有高滴度抗腺病毒抗体的马血浆来控制。细菌通过适当的抗生素治疗来控制。卡氏肺孢子虫感染在患有CID的马驹饲养过程中仍然是一个重大问题。
