Gershon Richard C, Rothrock Nan, Hanrahan Rachel, Bass Michael, Cella David
Department of Medical Social Sciences, Northwestern University, Chicago, IL 60611, USA.
J Appl Meas. 2010;11(3):304-14.
The Patient-Reported Outcomes Measurement Information System (PROMIS) was developed as one of the first projects funded by the NIH Roadmap for Medical Research Initiative to re-engineer the clinical research enterprise. The primary goal of PROMIS is to build item banks and short forms that measure key health outcome domains that are manifested in a variety of chronic diseases which could be used as a "common currency" across research projects. To date, item banks, short forms and computerized adaptive tests (CAT) have been developed for 13 domains with relevance to pediatric and adult subjects. To enable easy delivery of these new instruments, PROMIS built a web-based resource (Assessment Center) for administering CATs and other self-report data, tracking item and instrument development, monitoring accrual, managing data, and storing statistical analysis results. Assessment Center can also be used to deliver custom researcher developed content, and has numerous features that support both simple and complicated accrual designs (branching, multiple arms, multiple time points, etc.). This paper provides an overview of the development of the PROMIS item banks and details Assessment Center functionality.
患者报告结局测量信息系统（PROMIS）是美国国立卫生研究院医学研究路线图倡议资助的首批项目之一，旨在对临床研究企业进行重新设计。PROMIS的主要目标是建立条目库和简表，以测量在多种慢性病中表现出的关键健康结局领域，这些领域可作为跨研究项目的“通用货币”。迄今为止，已经针对与儿科和成人受试者相关的13个领域开发了条目库、简表和计算机自适应测试（CAT）。为了便于提供这些新工具，PROMIS建立了一个基于网络的资源（评估中心），用于管理CAT和其他自我报告数据、跟踪条目和工具的开发、监测入组情况、管理数据以及存储统计分析结果。评估中心还可用于提供研究人员定制开发的内容，并且具有许多支持简单和复杂入组设计（分支、多组、多个时间点等）的功能。本文概述了PROMIS条目库的开发情况，并详细介绍了评估中心的功能。
