Department of Respiratory Medicine, Baranya County Hospital, 2 Rákóczi street, Pécs 7623, Hungary.
Pathol Oncol Res. 2011 Jun;17(2):393-5. doi: 10.1007/s12253-010-9299-x. Epub 2010 Sep 17.
The spectrum of human diseases caused by members of the Aspergillus genus is extensive. It ranges from allergic reactions to colonization of preexisting pulmonary cavities to invasion and destruction of lung parenchyma with pyemic spread to brain, skin, and other organs, causing rapid death. The immune status of the host is a crucial factor in determining the phenotype and severity of the disease. In this case report Chronic Necrotizing Pulmonary Aspergillosis (CNPA), a rare, locally- or semi-invasive variant of pulmonary Aspergillosis, mimicking lung metastasis is presented. The 60-year-old male patient had earlier received multiple cycles of systemic chemotherapy due to colorectal carcinoma. Our case report focuses on the benefits and the possible disadvantages of PET-CT imaging in CNPA.
由曲霉属成员引起的人类疾病谱广泛。它从过敏反应到先前存在的肺空洞的定植,再到肺实质的侵袭和破坏,伴有脓毒性播散到大脑、皮肤和其他器官,导致迅速死亡。宿主的免疫状态是决定疾病表型和严重程度的关键因素。在本病例报告中,呈现了一种罕见的、局部或半侵袭性的肺部曲霉病,即慢性坏死性肺曲霉病(CNPA),模仿肺转移。这名 60 岁的男性患者因结直肠癌接受了多轮全身化疗。我们的病例报告重点介绍了 PET-CT 成像在 CNPA 中的益处和可能的弊端。