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与早产儿持续性肝静脉导管未闭相关的肝结节性病变。

Transient hepatic nodular lesions associated with patent ductus venosus in preterm infants.

机构信息

Unità Complessa di Pediatria e Terapia Intensiva Neonatale, Dipartimento Universitario Materno Infantile, Università degli Studi di Palermo, Via Alfonso Giordano 3, Palermo, Italy.

出版信息

Am J Perinatol. 2011 Mar;28(3):177-80. doi: 10.1055/s-0030-1265829. Epub 2010 Sep 16.

DOI:10.1055/s-0030-1265829
PMID:20848372
Abstract

We report on two cases of low-birth-weight preterm infants with patent ductus venosus associated with hepatic hypoechoic lesions of the fourth segment in an otherwise normal liver. Although tumorlike hepatic lesions have been previously reported in association with portosystemic shunts in children and adults, they were never described in preterm infants during physiological patency of ductus venosus. In our patients, hepatic lesions disappeared shortly after the spontaneous ductus closure. Physiopathologic interactions are discussed regarding altered portal blood supply caused by ductus venosus shunt.

摘要

我们报告了两例低出生体重早产儿,他们的脐静脉导管持续开放,且伴有第四段肝回声减弱。尽管此前曾有报道称,在儿童和成人的门体分流中存在类似肿瘤的肝病变,但在生理性脐静脉导管开放的早产儿中从未有过相关描述。在我们的患者中,肝病变在脐静脉导管自然闭合后不久即消失。我们讨论了由于脐静脉分流引起的门静脉血液供应改变所导致的病理生理相互作用。

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Transient hepatic nodular lesions associated with patent ductus venosus in preterm infants.与早产儿持续性肝静脉导管未闭相关的肝结节性病变。
Am J Perinatol. 2011 Mar;28(3):177-80. doi: 10.1055/s-0030-1265829. Epub 2010 Sep 16.
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Curr Cardiol Rev. 2019;15(3):167-176. doi: 10.2174/1573403X15666190115142303.
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Patent Ductus Venosus and Congenital Heart Disease: A Case Report and Review.静脉导管未闭与先天性心脏病:一例报告及文献复习
Cardiol Res. 2018 Oct;9(5):330-333. doi: 10.14740/cr777w. Epub 2018 Oct 7.
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Intrauterine growth restriction and congenital malformations: a retrospective epidemiological study.
宫内生长受限与先天性畸形:一项回顾性流行病学研究。
Ital J Pediatr. 2013 Apr 11;39:23. doi: 10.1186/1824-7288-39-23.
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Inherited liver shunts in dogs elucidate pathways regulating embryonic development and clinical disorders of the portal vein.遗传性犬肝脏分流阐明了调节胚胎发育和门静脉临床疾病的途径。
Mamm Genome. 2012 Feb;23(1-2):76-84. doi: 10.1007/s00335-011-9364-0. Epub 2011 Nov 4.