Department of Nuclear Medicine, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, 600 Yishan Road, Shanghai 200233, China.
Head Neck. 2011 Feb;33(2):171-7. doi: 10.1002/hed.21416.
Parapharyngeal metastasis is a rare event in differentiated thyroid carcinoma (DTC). The (131) I-single photon emission CT (SPECT)/CT allows better localization and definition for metastases in DTC. The aim of this study was to assess the value of (131) I-SPECT/CT for the diagnosis of parapharyngeal metastasis in patients with DTC.
Consecutive patients with DTC (n = 561) treated with (131) I for the ablation of remnant or treatment of metastases were enrolled. A (131) I-SPECT/CT was performed when there were abnormal findings indicative of parapharyngeal metastasis on (131) I-whole-body scan (WBS).
A total of 15 lesions were found to be parapharyngeal metastasis in 14 of 561 patients with DTC after the use of (131) I-SPECT/CT. The incidence rate of parapharyngeal metastasis was about 2.5% in DTC. Of the 15 lesions, only 5 lesions were CT-positive. The remaining 10 lesions were either ignored or indeterminate by the CT alone.
The (131) I-SPECT/CT can identify parapharyngeal metastasis at an early stage. Parapharyngeal metastasis in DTC is relatively frequent after the use of (131) I-SPECT/CT.
副神经节转移是分化型甲状腺癌（DTC）的罕见事件。碘-131 单光子发射计算机断层扫描（SPECT）/计算机断层扫描（CT）可更好地定位和定义 DTC 转移。本研究旨在评估碘-131-SPECT/CT 对 DTC 患者副神经节转移的诊断价值。
连续入组 561 例接受碘-131 消融残余或治疗转移的 DTC 患者。当 131I 全身扫描（WBS）发现提示副神经节转移的异常表现时，进行碘-131-SPECT/CT。
在 561 例 DTC 患者中，使用碘-131-SPECT/CT 后发现 14 例共 15 个病灶为副神经节转移。DTC 副神经节转移的发生率约为 2.5%。在 15 个病灶中，仅 5 个病灶 CT 阳性。其余 10 个病灶单独 CT 检查未显示或结果不确定。
碘-131-SPECT/CT 可早期识别副神经节转移。DTC 患者使用碘-131-SPECT/CT 后，副神经节转移较为常见。
