Department of Bioscience and Biotechnology, Bio/Molecular Informatics Center, Konkuk University, 1 Hwayang-dong Gwangjin-gu, Seoul 143-701, South Korea.
Carbohydr Res. 2010 Nov 2;345(16):2408-12. doi: 10.1016/j.carres.2010.08.009. Epub 2010 Aug 27.
A carboxymethylated cyclosophoraose (CM-Cys) was synthesized by the chemical modification of neutral Cys, which was isolated from Rhizobium trifolii TA-1. CM-Cys was successfully applied as a novel chiral selector for the separation of some flavonoids including catechin, 3,5,7,3',4'-pentahydroxyflavanone, hesperidin, hesperetin, isosakuranetin, naringenin, naringin, and eriodictyol. The effects of pH, chiral additive concentration, and temperature on resolution and migration time were also studied.
一种羧甲基化环 Sophora 糖（CM-Cys）通过三叶草根瘤菌 TA-1 中分离得到的中性半胱氨酸的化学修饰合成。CM-Cys 成功地用作一种新型手性选择剂，用于分离一些类黄酮，包括儿茶素、3,5,7,3',4'-五羟基黄酮酮、橙皮苷、橙皮苷、异圣草素、柚皮苷、柚皮苷和圣草酚。还研究了 pH 值、手性添加剂浓度和温度对拆分和迁移时间的影响。
