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[微生物学研究对诊断肠炎后反应性关节炎的价值]

[Value of microbiologic studies for diagnosis of post-enteritis reactive arthritis].

作者信息

Müller K D

机构信息

Institut für Medizinische Mikrobiologie, Universitätsklinikum Essen.

出版信息

Z Rheumatol. 1990 Nov-Dec;49(6):364-8.

PMID:2085058
Abstract

Reactive arthritis may develop within a period of some days until upto 3 weeks after infections with Yersinia enterocolitica, Yersinia pseudotuberculosis, Campylobacter jejuni/coli, Shigella and Salmonella. Intestinal infections with Klebsiella pneumoniae, Clostridium perfringens, Clostridium difficile, Cryptosporidium, Strongyloides stercoralis, Taenia saginata and Schistosoma mansoni are, in some cases, considered to be responsible for reactive arthritis. Detection of pathogenic bacteria in feces is generally most successful in the early stage of the infection. A large spectrum of special tests is required in order to detect all the causative agents and to ensure reliable results. It is therefore necessary that the laboratory is provided with information about the diagnostic object and the tentative diagnosis. The detection of serum antibodies to Y. enterocolitica, Y. pseudotuberculosis, C. jejuni/coli, and Schistosoma may suggest connections between infection and reactive arthritis.

摘要

反应性关节炎可能在感染小肠结肠炎耶尔森菌、假结核耶尔森菌、空肠弯曲菌/结肠弯曲菌、志贺菌和沙门菌后的数天至长达3周内发病。肺炎克雷伯菌、产气荚膜梭菌、艰难梭菌、隐孢子虫、粪类圆线虫、牛带绦虫和曼氏血吸虫引起的肠道感染,在某些情况下被认为与反应性关节炎有关。在感染早期,粪便中病原菌的检测通常最为成功。为了检测所有病原体并确保结果可靠,需要进行大量的特殊检测。因此,有必要向实验室提供有关诊断对象和初步诊断的信息。检测针对小肠结肠炎耶尔森菌、假结核耶尔森菌、空肠弯曲菌/结肠弯曲菌和血吸虫的血清抗体,可能提示感染与反应性关节炎之间的关联。

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